Articles

CT texture analysis: a potential tool for predicting the Fuhrman grade of clear-cell renal carcinoma

The purpose of this study was to analyze the image heterogeneity of clear-cell renal-cell carcinoma (ccRCC) by computer tomography texture analysis and to provide new objective quantitative imaging parameters ...

Authors: Zhan Feng, Qijun Shen, Ying Li and Zhengyu Hu

The utility of MRI histogram and texture analysis for the prediction of histological diagnosis in head and neck malignancies

To assess the utility of histogram and texture analysis of magnetic resonance (MR) fat-suppressed T2-weighted imaging (Fs-T2WI) for the prediction of histological diagnosis of head and neck squamous cell carci...

Authors: Noriyuki Fujima, Akihiro Homma, Taisuke Harada, Yukie Shimizu, Khin Khin Tha, Satoshi Kano, Takatsugu Mizumachi, Ruijiang Li, Kohsuke Kudo and Hiroki Shirato

Prediction of high nodal burden with ultrasound and magnetic resonance imaging in clinically node-negative breast cancer patients

Although the role of axillary imaging has been redirected for predicting high nodal burden rather than predicting nodal metastases since ACOSOG Z1011 trial, it remains unclear whether and how axillary lymph no...

Authors: Won Hwa Kim, Hye Jung Kim, So Mi Lee, Seung Hyun Cho, Kyung Min Shin, Sang Yub Lee and Jae Kwang Lim

Computed tomographic features of adenoid cystic carcinoma in the palate

To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.

Authors: Wu-tong Ju, Tong-chao Zhao, Ying Liu, Yi-ran Tan, Min-jun Dong, Qi Sun, Li-zhen Wang, Jiang Li and Lai-ping Zhong

Distribution of metastasis in the brain in relation to the hippocampus: a retrospective single-center analysis of 565 metastases in 116 patients

To examine the distribution of brain metastases (BM) in relation to the hippocampus, so as to determine the risk of metastasis in the hippocampus, and thus provide experimental evidence for the hippocampal avo...

Authors: Qian Sun, Min Li, Gengming Wang, Hongbo Xu, Zelai He, Yongchun Zhou, Yan Zhou, Yufu Zhou, Hongwei Song and Hao Jiang

Whole-body diffusion-weighted MRI for operability assessment in patients with colorectal cancer and peritoneal metastases

Correct staging of patients with colorectal cancer is of utmost importance for the prediction of operability. Although computed tomography (CT) has a good overall performance, estimation of peritoneal cancer s...

Authors: Raphaëla Carmen Dresen, Sofie De Vuysere, Frederik De Keyzer, Eric Van Cutsem, Hans Prenen, Ragna Vanslembrouck, Gert De Hertogh, Albert Wolthuis, André D’Hoore and Vincent Vandecaveye

“Sentinel lymph node imaging with sequential SPECT/CT lymphoscintigraphy before and after neoadjuvant chemoradiotherapy in patients with cancer of the oesophagus or gastro-oesophageal junction – a pilot study”

In current best practise, curatively intended treatment for oesophageal cancer usually consists of neoadjuvant chemo-radiotherapy (nCRT) or perioperative chemotherapy, and oesophagectomy. Sentinel Lymph Node B...

Authors: Stefan Gabrielson, Jon A. Tsai, Fuat Celebioglu, Magnus Nilsson, Ioannis Rouvelas, Mats Lindblad, Annie Bjäreback, Artur Tomson and Rimma Axelsson

CT texture analysis of lung adenocarcinoma: can Radiomic features be surrogate biomarkers for EGFR mutation statuses

To investigate whether radiomic features can be surrogate biomarkers for epidermal growth factor receptor (EGFR) mutation statuses.

Authors: Dongdong Mei, Yan Luo, Yan Wang and Jingshan Gong

IDEAL-IQ in an oncologic population: meeting the challenge of concomitant liver fat and liver iron

Cancer patients often have a history of chemotherapy, putting them at increased risk of liver toxicity and pancytopenia, leading to elevated liver fat and elevated liver iron respectively. T1-in-and-out-of-pha...

Authors: Sarah Eskreis-Winkler, Giuseppe Corrias, Serena Monti, Junting Zheng, Marinela Capanu, Simone Krebs, Maggie Fung, Scott Reeder and Lorenzo Mannelli

Discrepancies of assessments in a RECIST 1.1 phase II clinical trial – association between adjudication rate and variability in images and tumors selection

In imaging-based clinical trials, it is common practice to perform double reads for each image, discrepant interpretations can result from these two different evaluations. In this study we analyzed discrepanci...

Authors: Hubert Beaumont, Tracey L. Evans, Catherine Klifa, Ali Guermazi, Sae Rom Hong, Mustapha Chadjaa and Zsuzsanna Monostori

Preoperative prediction of peripancreatic vein invasion by pancreatic head cancer

Pancreatic adenocarcinoma is often diagnosed at an advanced stage when adjacent vascular invasion is present. Accurate evaluation of presence of vascular invasion can help guide therapy. The aim of this study ...

Authors: Yi-Nan Shen, Cheng-Xiang Guo, Yao Pan, Yi-Wen Chen, Tian-Yu Tang, Yu-Wei Li, Jun-Hua Lu, Gang Jin, Ren-Yi Qin, Wei-Yun Yao, Ting-Bo Liang and Xue-Li Bai

Comparison of gadoxetic acid versus gadopentetate dimeglumine for the detection of hepatocellular carcinoma at 1.5 T using the liver imaging reporting and data system (LI-RADS v.2017)

The goal of this study was to investigate the Liver Imaging Reporting and Data System (LI-RADS) v.2017 for the categorization of hepatocellular carcinomas (HCCs) with gadoxetic acid compared with gadopentetate...

Authors: Ying Ding, Sheng-xiang Rao, Wen-tao Wang, Cai-zhong Chen, Ren-chen Li and Mengsu Zeng

The eye of the beholder: orbital metastases from midgut neuroendocrine tumors, a two institution experience

Metastases to the orbit occur rarely in midgut neuroendocrine tumor (NET) patients with only 20 cases reported to date. Patients typically present with bilateral involvement of the recti muscles and experience...

Authors: Satya Das, Gino Pineda, Laura Goff, Rachel Sobel, Jordan Berlin and George Fisher

Tumor heterogeneity in gastrointestinal stromal tumors of the small bowel: volumetric CT texture analysis as a potential biomarker for risk stratification

To explore whether volumetric CT texture analysis (CTTA) can serve as a potential imaging biomarker for risk stratification of small bowel gastrointestinal stromal tumors (small bowel-GISTs).

Authors: Cui Feng, Fangfang Lu, Yaqi Shen, Anqin Li, Hao Yu, Hao Tang, Zhen Li and Daoyu Hu

Endometrial cancer: an overview of novelties in treatment and related imaging keypoints for local staging

Endometrial cancer is the most common gynaecologic malignancy in developed countries and its incidence is increasing. First-level treatment, if no contraindicated, is based on surgery. Pre-operative imaging is...

Authors: Stefania Rizzo, Marco Femia, Valentina Buscarino, Dorella Franchi, Annalisa Garbi, Vanna Zanagnolo, Maria Del Grande, Lucia Manganaro, Sarah Alessi, Caterina Giannitto, Francesca Ruju and Massimo Bellomi

Mono, bi- and tri-exponential diffusion MRI modelling for renal solid masses and comparison with histopathological findings

To compare diffusion tensor imaging (DTI), intravoxel incoherent motion (IVIM), and tri-exponential models of the diffusion magnetic resonance imaging (MRI) signal for the characterization of renal lesions in ...

Authors: Sophie van Baalen, Martijn Froeling, Marino Asselman, Caroline Klazen, Claire Jeltes, Lotte van Dijk, Bart Vroling, Pieter Dik and Bennie ten Haken

Diffusion-weighted imaging of rectal cancer on repeatability and cancer characterization: an effect of b-value distribution study

To explore the effect of b-value distributions on the repeatability and diagnostic performance of the ADC value in rectal cancer patients using multiple b-values and mono-exponential model diffusion-weighted i...

Authors: Luguang Chen, Fu Shen, Zhihui Li, Haidi Lu, Yukun Chen, Zhen Wang and Jianping Lu

Detection of gastric cancer and its histological type based on iodine concentration in spectral CT

Computed tomography (CT) imaging is the most common imaging modality for the diagnosis and staging of gastric cancer. The aim of this study is was to prospectively explore the ability of quantitative spectral ...

Authors: Rui Li, Jing Li, Xiaopeng Wang, Pan Liang and Jianbo Gao

Evaluation of pancreatic tumor development in KPC mice using multi-parametric MRI

Pancreatic ductal adenocarcinoma (PDA) is a fatal disease with very poor prognosis. Development of sensitive and noninvasive methods to monitor tumor progression in PDA is a critical and unmet need. Magnetic r...

Authors: Ravneet Vohra, Joshua Park, Yak-Nam Wang, Kayla Gravelle, Stella Whang, Joo-Ha Hwang and Donghoon Lee

Pain control for patients with hepatocellular carcinoma undergoing CT-guided percutaneous microwave ablation

Hepatic percutaneous microwave ablation (MWA) is usually performed in patients under conscious sedation. Nonetheless, many patients reported pain during the procedure. The current study investigated the safety...

Authors: Hong-Zhi Zhang, Jie Pan, Jing Sun, Yu-Mei Li, Kang Zhou, Yang Li, Jin Cheng, Ying Wang, Dong-Lei Shi and Shao-Hui Chen

68Ga-PSMA PET/CT in prostate cancer patients – patterns of disease, benign findings and pitfalls

68Ga-PSMA PET/CT has an important role in assessment of prostate cancer patients with biochemical recurrence and is evolving in staging high- and intermediate risk disease. The aim of present study was to desc...

Authors: Zohar Keidar, Ronit Gill, Elinor Goshen, Ora Israel, Tima Davidson, Maryna Morgulis, Natalia Pirmisashvili and Simona Ben-Haim

Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy

It is very difficult to predict the early response to NAC only on the basis of change in tumor size. ADC value derived from DWI promises to be a valuable parameter for evaluating the early response to treatmen...

Authors: Li Yuan, Jian-Jun Li, Chang-Qing Li, Cheng-Gong Yan, Ze-Long Cheng, Yuan-Kui Wu, Peng Hao, Bing-Quan Lin and Yi-Kai Xu

The differentiation of pancreatic neuroendocrine carcinoma from pancreatic ductal adenocarcinoma: the values of CT imaging features and texture analysis

Imaging findings for pancreatic neuroendocrine carcinoma (PNEC) and pancreatic ductal adenocarcinoma (PDAC) often overlap. The aim of this study was to demonstrate the value of computed tomography (CT) imaging...

Authors: Chuangen Guo, Xiaoling Zhuge, Qidong Wang, Wenbo Xiao, Zhonglan Wang, Zhongqiu Wang, Zhan Feng and Xiao Chen

Imaging and clinical features of primary hepatic sarcomatous carcinoma

Primary hepatic sarcomatous carcinoma (PHSC) is a rare malignancy composed of both carcinomatous (either hepatocellular or cholangiocellular) and sarcomatous components. The purpose of our study was to evaluat...

Authors: Dongli Shi, Liang Ma, Dawei Zhao, Jing Chang, Chen Shao, Shi Qi, Feng Chen, Yunfang Li, Xing Wang, Yanyan Zhang, Jing Zhao and Hongjun Li

Accurate FDG PET tumor segmentation using the peritumoral halo layer method: a study in patients with esophageal squamous cell carcinoma

In a previous study, FDG PET tumor segmentation (SegPHL) using the peritumoral halo layer (PHL) was more reliable than fixed threshold methods in patients with thyroid cancer. We performed this study to valida...

Authors: Sungmin Jun, Jung Gu Park and Youngduk Seo

Identification and characterization of myocardial metastases in neuroendocrine tumor patients using 68Ga-DOTATATE PET-CT

Focal 68Ga-DOTATATE PET lesions within the myocardium of neuroendocrine tumor (NET) patients are observed in clinical practice. We determined the frequency and characteristics of lesions that are consistent wi...

Authors: Wolfgang G. Kunz, Ralf S. Eschbach, Robert Stahl, Philipp M. Kazmierczak, Peter Bartenstein, Axel Rominger, Christoph J. Auernhammer, Christine Spitzweg, Jens Ricke and Clemens C. Cyran

Findings of DTI-p maps in comparison with T₂/T₂-FLAIR to assess postoperative hyper-signal abnormal regions in patients with glioblastoma

The aim of this study was to compare diffusion tensor imaging (DTI) isotropic map (p-map) with current radiographically (T₂/T₂-FLAIR) methods based on abnormal hyper-signal size and location of glioblastoma tumor...

Authors: Manijeh Beigi, Mojtaba Safari, Ahmad Ameri, Mohsen Shojaee Moghadam, Azim Arbabi, Morteza Tabatabaeefar and Hamidreza SalighehRad

Accuracy of F-18 FDG PET/CT with optimal cut-offs of maximum standardized uptake value according to size for diagnosis of regional lymph node metastasis in patients with rectal cancer

The low sensitivity of F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for the evaluation of metastatic lymph nodes (LNs) is mainly due to the partial volume effect in p...

Authors: Sung Uk Bae, Kyoung Sook Won, Bong-Il Song, Woon Kyung Jeong, Seong Kyu Baek and Hae Won Kim

Retraction Note: Pre-treatment DWI as a predictor of overall survival in locally advanced pancreatic cancer treated with Cyberknife radiotherapy and sequential S-1 therapy

The authors have retracted this article because Figs. 2, 3 and 4, as well as parts of the text have been previously published [1]. This article is therefore redundant. Yu Zhang, Denghui Liu, Jiaqi Song, Huojun...

Authors: Yu Zhang, Xiaofei Zhu, Denghui Liu, Jiaqi Song, Huojun Zhang and Jianping Lu

Proceedings of the International Cancer Imaging Society (ICIS) 18th Annual Teaching Course

Authors:

Risk of renal events following intravenous iodinated contrast material administration among inpatients admitted with cancer a retrospective hospital claims analysis

There is little published evidence examining the use of contrast material (CM) and the risk of acute renal adverse events (AEs) in individuals with increasingly common risk factors including cancer and chronic...

Authors: Chaan S. Ng, Sanjeeva P. Kalva, Candace Gunnarsson, Michael P. Ryan, Erin R. Baker and Ravindra L. Mehta

Castleman disease versus lymphoma in neck lymph nodes: a comparative study using contrast-enhanced CT

The purpose of this study was to determine the contrast-enhanced CT characteristics for differentiating between Castleman disease (CD) and lymphoma in neck lymph nodes.

Authors: Jie Li, Jia Wang, Zhitao Yang, Hexiang Wang, Junyi Che and Wenjian Xu

Whole-body magnetic resonance imaging of Li-Fraumeni syndrome patients: observations from a two rounds screening of Brazilian patients

Li-Fraumeni syndrome (LFS) is an autosomal dominant disease that is associated with germline TP53 mutations and it predisposes affected individuals to a high risk of developing multiple tumors. In Brazil, LFS is ...

Authors: Daniele Paixão, Marcos Duarte Guimarães, Kelvin César de Andrade, Amanda França Nóbrega, Rubens Chojniak and Maria Isabel Achatz

Gastric heterotopic pancreas and stromal tumors smaller than 3 cm in diameter: clinical and computed tomography findings

Identifying gastric heterotopic pancreas and stromal tumors is difficult. Few studies have reported computed tomography (CT) findings for differentiating lesions less than 3 cm in diameter. In this study, we a...

Authors: Li-ming Li, Lei-yu Feng, Xiao-hua Chen, Pan Liang, Jing Li and Jian-bo Gao

¹¹C-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial)

To evaluate the accuracy of ¹¹C-acetate Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) in bladder cancer (BC) staging and monitoring response to neoadjuvant chemotherapy (NAC).

Authors: Antti Salminen, Ivan Jambor, Harri Merisaari, Otto Ettala, Johanna Virtanen, Ilmari Koskinen, Erik Veskimae, Jukka Sairanen, Pekka Taimen, Jukka Kemppainen, Heikki Minn and Peter J. Boström

Clinical efficacy of chemoembolization with simultaneous radiofrequency ablation for treatment of adrenal metastases from hepatocellular carcinoma

This study investigated the safety and efficacy of transcatheter arterial chemoembolization (TACE) with simultaneous radiofrequency ablation (RFA) as treatment for adrenal metastases (AM) from hepatocellular c...

Authors: Hongjun Yuan, Fengyong Liu, Xin Li, Yang Guan and Maoqiang Wang

The utility of measuring the apparent diffusion coefficient for peritumoral zone in assessing infiltration depth of endometrial cancer

The invasion depth of endometrial cancer is one of the most important prognosis factors. The aim of the current study was to investigate the diagnostic value of the apparent diffusion coefficient (ADC) of the ...

Authors: Lei Deng, Qiu-ping Wang, Rui Yan, Xiao-yi Duan, Lu Bai, Nan Yu, You-min Guo and Quan-xin Yang

CT during celiac artery angiography for localization of clinically suspected small insulinomas

To identify location and number of insulinomas before operation is very important for improving the cure rate. The objective of the study was to assess performance of CT during celiac artery angiography for pr...

Authors: Feng Duan, Yan-hua Bai, Li Cui, Jie-yu Yan, Xiao-hui Li and Xiu-qi Wang

Fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI for predicting small node metastases in patients with rectal cancer

To investigate the application value of fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI in regional nodes with different short-axis diameter ranges in rectal cancer, especially in node...

Authors: Yan Chen, Xinyue Yang, Ziqiang Wen, Baolan Lu, Xiaojuan Xiao, Bingqi Shen and Shenping Yu

⁶⁸ Ga-PSMA-PET/CT for the evaluation of pulmonary metastases and opacities in patients with prostate cancer

The purpose of this study was to investigate the imaging properties of pulmonary metastases and benign opacities in ⁶⁸Ga-PSMA positron emission tomography (PET) in patients with prostate cancer (PC).

Authors: Jonathan Damjanovic, Jan-Carlo Janssen, Christian Furth, Gerd Diederichs, Thula Walter, Holger Amthauer and Marcus R. Makowski

The role of initial ¹⁸F-FDG PET/CT in the management of patients with suspected extramedullary plasmocytoma

Extramedullary plasmacytoma (EMP) is a plasma cell malignancy that originates in soft tissues without evidence of systemic spread, and its management differs from other plasma cell neoplasms. The purpose of th...

Authors: Linqi Zhang, Xu Zhang, Qiao He, Rusen Zhang and Wei Fan

Solid component proportion is an important predictor of tumor invasiveness in clinical stage T₁N₀M₀ (cT₁N₀M₀) lung adenocarcinoma

Preoperative tumor invasiveness in clinical stage T₁N₀M₀ lung adenocarcinoma is critical for optimal surgical procedure. The aim of the present study was to evaluate the relationship between the ground-glass opac...

Authors: Meng Li, Ning Wu, Li Zhang, Wei Sun, Ying Liu, Lv Lv, Jiansong Ren and Dongmei Lin

Renal cell carcinoma with venous extension: prediction of inferior vena cava wall invasion by MRI

Renal cell carcinoma (RCC) are accompanied by inferior vena cava (IVC) thrombus in up to 10% of the cases, with surgical resection remaining the only curative option. In case of IVC wall invasion, the operativ...

Authors: Lisa C. Adams, Bernhard Ralla, Yi-Na Y. Bender, Keno Bressem, Bernd Hamm, Jonas Busch, Florian Fuller and Marcus R. Makowski

Image quality of arterial phase and parenchymal blood volume (PBV) maps derived from C-arm computed tomography in the evaluation of transarterial chemoembolization

To evaluate the benefits of arterial phase imaging and parenchymal blood volume (PBV) maps acquired by C-arm computed tomography during TACE procedure in comparison to cross-sectional imaging (CSI) using CT or...

Authors: Tanja Zitzelsberger, Roland Syha, Gerd Grözinger, Sasan Partovi, Konstantin Nikolaou and Ulrich Grosse

An international survey on hybrid imaging: do technology advances preempt our training and education efforts?

Hybrid PET/CT and PET/MRI are increasingly important technologies in the evaluation of malignancy and require cooperation between radiologists and specialists in molecular imaging. The aim of our study was to ...

Authors: T. Beyer, R. Hicks, C. Brun, G. Antoch and L. S. Freudenberg

LI-RADS v2017 for liver nodules: how we read and report

The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation and reporting of imaging examinations in patients at risk for hepatocellular carcinoma (HCC). For focal liver observations ...

Authors: Wolfgang Schima and Jay Heiken

Review of targeted therapy in chronic lymphocytic leukemia: what a radiologist needs to know about CT interpretation

The last 5 years have been marked by profound innovation in the targeted treatment of chronic lymphocytic leukemia (CLL) and indolent lymphomas. Using CLL as a case study, we present a timeline and overview of...

Authors: Babina Gosangi, Matthew Davids, Bhanusupriya Somarouthu, Francesco Alessandrino, Angela Giardino, Nikhil Ramaiya and Katherine Krajewski

Most-enhancing tumor volume by MRI radiomics predicts recurrence-free survival “early on” in neoadjuvant treatment of breast cancer

The hypothesis of this study was that MRI-based radiomics has the ability to predict recurrence-free survival “early on” in breast cancer neoadjuvant chemotherapy.

Authors: Karen Drukker, Hui Li, Natalia Antropova, Alexandra Edwards, John Papaioannou and Maryellen L. Giger

Ultrasound shear wave elastography of breast lesions: correlation of anisotropy with clinical and histopathological findings

Ultrasound shear-wave elastography (SWE) may increase specificity of breast lesion assessment with ultrasound, but elasticity measurements may change with transducer orientation, defined as anisotropy. In this...

Authors: Ya-ling Chen, Yi Gao, Cai Chang, Fen Wang, Wei Zeng and Jia-jian Chen

Added value of diffusion-weighted imaging in hepatic tumors and its impact on patient management

To investigate the added diagnostic value of diffusion-weighted imaging (DWI) of the liver and its impact on therapy decisions in patients with hepatic malignancy.

Authors: Jana Taron, Jonas Johannink, Michael Bitzer, Konstantin Nikolaou, Mike Notohamiprodjo and Rüdiger Hoffmann