Articles

Castleman disease versus lymphoma in neck lymph nodes: a comparative study using contrast-enhanced CT

The purpose of this study was to determine the contrast-enhanced CT characteristics for differentiating between Castleman disease (CD) and lymphoma in neck lymph nodes.

Authors: Jie Li, Jia Wang, Zhitao Yang, Hexiang Wang, Junyi Che and Wenjian Xu

Whole-body magnetic resonance imaging of Li-Fraumeni syndrome patients: observations from a two rounds screening of Brazilian patients

Li-Fraumeni syndrome (LFS) is an autosomal dominant disease that is associated with germline TP53 mutations and it predisposes affected individuals to a high risk of developing multiple tumors. In Brazil, LFS is ...

Authors: Daniele Paixão, Marcos Duarte Guimarães, Kelvin César de Andrade, Amanda França Nóbrega, Rubens Chojniak and Maria Isabel Achatz

Gastric heterotopic pancreas and stromal tumors smaller than 3 cm in diameter: clinical and computed tomography findings

Identifying gastric heterotopic pancreas and stromal tumors is difficult. Few studies have reported computed tomography (CT) findings for differentiating lesions less than 3 cm in diameter. In this study, we a...

Authors: Li-ming Li, Lei-yu Feng, Xiao-hua Chen, Pan Liang, Jing Li and Jian-bo Gao

¹¹C-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial)

To evaluate the accuracy of ¹¹C-acetate Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) in bladder cancer (BC) staging and monitoring response to neoadjuvant chemotherapy (NAC).

Authors: Antti Salminen, Ivan Jambor, Harri Merisaari, Otto Ettala, Johanna Virtanen, Ilmari Koskinen, Erik Veskimae, Jukka Sairanen, Pekka Taimen, Jukka Kemppainen, Heikki Minn and Peter J. Boström

Clinical efficacy of chemoembolization with simultaneous radiofrequency ablation for treatment of adrenal metastases from hepatocellular carcinoma

This study investigated the safety and efficacy of transcatheter arterial chemoembolization (TACE) with simultaneous radiofrequency ablation (RFA) as treatment for adrenal metastases (AM) from hepatocellular c...

Authors: Hongjun Yuan, Fengyong Liu, Xin Li, Yang Guan and Maoqiang Wang

The utility of measuring the apparent diffusion coefficient for peritumoral zone in assessing infiltration depth of endometrial cancer

The invasion depth of endometrial cancer is one of the most important prognosis factors. The aim of the current study was to investigate the diagnostic value of the apparent diffusion coefficient (ADC) of the ...

Authors: Lei Deng, Qiu-ping Wang, Rui Yan, Xiao-yi Duan, Lu Bai, Nan Yu, You-min Guo and Quan-xin Yang

CT during celiac artery angiography for localization of clinically suspected small insulinomas

To identify location and number of insulinomas before operation is very important for improving the cure rate. The objective of the study was to assess performance of CT during celiac artery angiography for pr...

Authors: Feng Duan, Yan-hua Bai, Li Cui, Jie-yu Yan, Xiao-hui Li and Xiu-qi Wang

Fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI for predicting small node metastases in patients with rectal cancer

To investigate the application value of fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI in regional nodes with different short-axis diameter ranges in rectal cancer, especially in node...

Authors: Yan Chen, Xinyue Yang, Ziqiang Wen, Baolan Lu, Xiaojuan Xiao, Bingqi Shen and Shenping Yu

⁶⁸ Ga-PSMA-PET/CT for the evaluation of pulmonary metastases and opacities in patients with prostate cancer

The purpose of this study was to investigate the imaging properties of pulmonary metastases and benign opacities in ⁶⁸Ga-PSMA positron emission tomography (PET) in patients with prostate cancer (PC).

Authors: Jonathan Damjanovic, Jan-Carlo Janssen, Christian Furth, Gerd Diederichs, Thula Walter, Holger Amthauer and Marcus R. Makowski

The role of initial ¹⁸F-FDG PET/CT in the management of patients with suspected extramedullary plasmocytoma

Extramedullary plasmacytoma (EMP) is a plasma cell malignancy that originates in soft tissues without evidence of systemic spread, and its management differs from other plasma cell neoplasms. The purpose of th...

Authors: Linqi Zhang, Xu Zhang, Qiao He, Rusen Zhang and Wei Fan

Solid component proportion is an important predictor of tumor invasiveness in clinical stage T₁N₀M₀ (cT₁N₀M₀) lung adenocarcinoma

Preoperative tumor invasiveness in clinical stage T₁N₀M₀ lung adenocarcinoma is critical for optimal surgical procedure. The aim of the present study was to evaluate the relationship between the ground-glass opac...

Authors: Meng Li, Ning Wu, Li Zhang, Wei Sun, Ying Liu, Lv Lv, Jiansong Ren and Dongmei Lin

Renal cell carcinoma with venous extension: prediction of inferior vena cava wall invasion by MRI

Renal cell carcinoma (RCC) are accompanied by inferior vena cava (IVC) thrombus in up to 10% of the cases, with surgical resection remaining the only curative option. In case of IVC wall invasion, the operativ...

Authors: Lisa C. Adams, Bernhard Ralla, Yi-Na Y. Bender, Keno Bressem, Bernd Hamm, Jonas Busch, Florian Fuller and Marcus R. Makowski

Image quality of arterial phase and parenchymal blood volume (PBV) maps derived from C-arm computed tomography in the evaluation of transarterial chemoembolization

To evaluate the benefits of arterial phase imaging and parenchymal blood volume (PBV) maps acquired by C-arm computed tomography during TACE procedure in comparison to cross-sectional imaging (CSI) using CT or...

Authors: Tanja Zitzelsberger, Roland Syha, Gerd Grözinger, Sasan Partovi, Konstantin Nikolaou and Ulrich Grosse

An international survey on hybrid imaging: do technology advances preempt our training and education efforts?

Hybrid PET/CT and PET/MRI are increasingly important technologies in the evaluation of malignancy and require cooperation between radiologists and specialists in molecular imaging. The aim of our study was to ...

Authors: T. Beyer, R. Hicks, C. Brun, G. Antoch and L. S. Freudenberg

LI-RADS v2017 for liver nodules: how we read and report

The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation and reporting of imaging examinations in patients at risk for hepatocellular carcinoma (HCC). For focal liver observations ...

Authors: Wolfgang Schima and Jay Heiken

Review of targeted therapy in chronic lymphocytic leukemia: what a radiologist needs to know about CT interpretation

The last 5 years have been marked by profound innovation in the targeted treatment of chronic lymphocytic leukemia (CLL) and indolent lymphomas. Using CLL as a case study, we present a timeline and overview of...

Authors: Babina Gosangi, Matthew Davids, Bhanusupriya Somarouthu, Francesco Alessandrino, Angela Giardino, Nikhil Ramaiya and Katherine Krajewski

Most-enhancing tumor volume by MRI radiomics predicts recurrence-free survival “early on” in neoadjuvant treatment of breast cancer

The hypothesis of this study was that MRI-based radiomics has the ability to predict recurrence-free survival “early on” in breast cancer neoadjuvant chemotherapy.

Authors: Karen Drukker, Hui Li, Natalia Antropova, Alexandra Edwards, John Papaioannou and Maryellen L. Giger

Ultrasound shear wave elastography of breast lesions: correlation of anisotropy with clinical and histopathological findings

Ultrasound shear-wave elastography (SWE) may increase specificity of breast lesion assessment with ultrasound, but elasticity measurements may change with transducer orientation, defined as anisotropy. In this...

Authors: Ya-ling Chen, Yi Gao, Cai Chang, Fen Wang, Wei Zeng and Jia-jian Chen

Added value of diffusion-weighted imaging in hepatic tumors and its impact on patient management

To investigate the added diagnostic value of diffusion-weighted imaging (DWI) of the liver and its impact on therapy decisions in patients with hepatic malignancy.

Authors: Jana Taron, Jonas Johannink, Michael Bitzer, Konstantin Nikolaou, Mike Notohamiprodjo and Rüdiger Hoffmann

Imaging features of fibrolamellar hepatocellular carcinoma in gadoxetic acid-enhanced MRI

Fibrolamellar hepatocellular carcinoma (FLC) is a rare malignancy occurring in young patients without cirrhosis. Objectives of our study were to analyze contrast material uptake in hepatobiliary phase imaging ...

Authors: Viktoria Palm, Ruofan Sheng, Philipp Mayer, Karl-Heinz Weiss, Christoph Springfeld, Arianeb Mehrabi, Thomas Longerich, Anne Katrin Berger, Hans-Ulrich Kauczor and Tim Frederik Weber

Primary carcinosarcoma of the liver: imaging features and clinical findings in six cases and a review of the literature

Carcinosarcoma of the liver is a very rare tumor composed of a mixture of carcinomatous and sarcomatous elements. Less than 25 adequately documented cases have been reported, with inadequate description of ima...

Authors: Jing Li, Pan Liang, Dandan Zhang, Jie Liu, Hongkai Zhang, Jinrong Qu and Jianbo Gao

MRI features of combined hepatocellular- cholangiocarcinoma versus mass forming intrahepatic cholangiocarcinoma

Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver tumor, which has overlapping imaging features with mass forming intra-hepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma ...

Authors: Jennifer Sammon, Sandra Fischer, Ravi Menezes, Hooman Hosseini-Nik, Sara Lewis, Bachir Taouli and Kartik Jhaveri

Pre-treatment DWI as a predictor of overall survival in locally advanced pancreatic cancer treated with Cyberknife radiotherapy and sequential S-1 therapy

To identify the value of the pre-treatment apparent diffusion coefficient (ADC) derived from diffusion weighted imaging (DWI) in predicting the overall survival (OS) for locally advanced pancreatic cancer (LAP...

Authors: Yu Zhang, Xiaofei Zhu, Denghui Liu, Jiaqi Song, Huojun Zhang and Jianping Lu

Cement pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients

Vertebroplasty is a minimally invasive procedure commonly performed for vertebral compression fractures secondary to osteoporosis or malignancy. Leakage of bone cement into the paravertebral venous system and ...

Authors: Asem Mansour, Nayef Abdel-Razeq, Hussein Abuali, Mohammad Makoseh, Nouran Shaikh-Salem, Kamelah Abushalha and Samer Salah

Diagnostic performance of ¹⁸F-FDG PET/CT using point spread function reconstruction on initial staging of rectal cancer: a comparison study with conventional PET/CT and pelvic MRI

Accurate staging is crucial for treatment selection and prognosis prediction in patients with rectal cancer. Point spread function (PSF) reconstruction can improve spatial resolution and signal-to-noise ratio ...

Authors: Masatoshi Hotta, Ryogo Minamimoto, Hideaki Yano, Yoshimasa Gohda and Yasutaka Shuno

Changes in biodistribution on ⁶⁸Ga-DOTA-Octreotate PET/CT after long acting somatostatin analogue therapy in neuroendocrine tumour patients may result in pseudoprogression

To evaluate the effects of long-acting somatostatin analogue (SSA) therapy on ⁶⁸Ga-DOTA-octreotate (GaTate) uptake at physiological and metastatic sites in neuroendocrine tumour (NET) patients.

Authors: Martin H. Cherk, Grace Kong, Rodney J. Hicks and Michael S. Hofman

¹⁸F–FDG-PET/CT and diffusion-weighted MRI for monitoring a BRAF and CDK 4/6 inhibitor combination therapy in a murine model of human melanoma

The purpose of the study was to investigate a novel BRAF and CDK 4/6 inhibitor combination therapy in a murine model of BRAF-V600-mutant human melanoma monitored by ¹⁸F–FDG-PET/CT and diffusion-weighted MRI (DW-M...

Authors: Ralf S. Eschbach, Philipp M. Kazmierczak, Maurice M. Heimer, Andrei Todica, Heidrun Hirner-Eppeneder, Moritz J. Schneider, Georg Keinrath, Olga Solyanik, Jessica Olivier, Wolfgang G. Kunz, Maximilian F. Reiser, Peter Bartenstein, Jens Ricke and Clemens C. Cyran

Identification of the pericardiacophrenic vein on CT

To evaluate the depictability of pericardiacophrenic veins (PCPV) as landmarks for the location of the phrenic nerves on multi-detector-row computed tomography (MDCT), and to investigate the usefulness of depi...

Authors: Yoshiyuki Ozawa, Ritsuko Suzuki, Masaki Hara and Yuta Shibamoto

⁶⁸Ga PSMA-11 PET with CT urography protocol in the initial staging and biochemical relapse of prostate cancer

⁶⁸Ga-labelled prostate specific membrane antigen (PSMA) ligand PET/CT is a promising modality in primary staging (PS) and biochemical relapse (BCR) of prostate cancer (PC). However, pe...

Authors: Amir Iravani, Michael S. Hofman, Tony Mulcahy, Scott Williams, Declan Murphy, Bimal K. Parameswaran and Rodney J. Hicks

Integration of CT urography improves diagnostic confidence of ⁶⁸Ga-PSMA-11 PET/CT in prostate cancer patients

To prove the feasibility of integrating CT urography (CTU) into ⁶⁸Ga-PSMA-11 PET/CT and to analyze the impact of CTU on assigning focal tracer accumulation in the ureteric space to either ureteric excretion or me...

Authors: Leon Will, Frederik L. Giesel, Martin T. Freitag, Anne K. Berger, Walter Mier, Klaus Kopka, Stefan A. Koerber, Hendrik Rathke, Christophe Kremer, Clemens Kratochwil, Hans-Ulrich Kauczor, Uwe Haberkorn and Tim F. Weber

3.0T MRI for long-term observation of lung nodules post cryoablation: a pilot study

The purpose of this study was to use serial magnetic resonance imaging (MRI) examinations to observe changes in malignant lung tumors over time post-cryoablation.

Authors: Jing Li, Jinrong Qu, Hongkai Zhang, Yingshu Wang, Lin Zheng, Xiang Geng, Yan Zhao and Hailiang Li

How we read pediatric PET/CT: indications and strategies for image acquisition, interpretation and reporting

PET/CT plays an important role in the diagnosis, staging and management of many pediatric malignancies. The techniques for performing PET/CT examinations in children have evolved, with increasing attention foc...

Authors: Gabrielle C. Colleran, Neha Kwatra, Leah Oberg, Frederick D. Grant, Laura Drubach, Michael J. Callahan, Robert D. MacDougall, Frederic H. Fahey and Stephan D. Voss

Comparison of efficacy and complications of endoscopic and percutaneous biliary drainage in malignant obstructive jaundice: a systematic review and meta-analysis

Malignant obstructive jaundice is a common problem in the clinic. Currently, the generally applied treatment methods are percutaneous transhepatic biliary drainage (PTBD) and endoscopic biliary drainage (EBD)....

Authors: Feng Duan, Li Cui, Yanhua Bai, Xiaohui Li, Jieyu Yan and Xuan Liu

Lymphomatosis cerebri: a rare variant of primary central nervous system lymphoma and MR imaging features

Lymphomatosis cerebri (LC) is a rare variant of primary central nervous system lymphoma (PCNSL), characterized by diffuse infiltration without the formation of a discrete mass. The diagnosis of LC is a challen...

Authors: Hui Yu, Bo Gao, Jing Liu, Yong-Cheng Yu, Mark S. Shiroishi, Ming-Ming Huang, Wen-Xiu Yang and Zhi-Zhong Guan

Portal vein embolization with n-butyl-cyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients

To evaluate the efficacy of portal vein embolization (PVE) with n-Butyl-cyanoacrylate (NBCA) through an ipsilateral approach before major hepatectomy. Secondary end-points were PVE safety, liver resection and ...

Authors: José Hugo Mendes Luz, Paula Mendes Luz, Tiago Bilhim, Henrique Salas Martin, Hugo Rodrigues Gouveia, Élia Coimbra, Filipe Veloso Gomes, Roberto Romulo Souza, Igor Murad Faria and Tiago Nepomuceno de Miranda

Proceedings of the International Cancer Imaging Society (ICIS) 17th Annual Teaching Course

Authors:

¹⁸F-FDG PET/CT response in a phase 1/2 trial of nab-paclitaxel plus gemcitabine for advanced pancreatic cancer

Positron emission tomography (PET) is poised to become a useful imaging modality in staging and evaluating therapeutic responses in patients with metastatic pancreatic cancer (mPC). This analysis from a phase ...

Authors: Ronald L. Korn, Daniel D. Von Hoff, Mitesh J. Borad, Markus F. Renschler, Desmond McGovern, R. Curtis Bay and Ramesh K. Ramanathan

Osteoradionecrosis of the hyoid bone after intra-arterial chemoradiotherapy for oropharyngeal cancer: MR imaging findings

Osteoradionecrosis (ORN) of the hyoid bone sometimes induces severe front neck infection and can cause laryngeal stenosis and carotid rupture. Although ORN of the hyoid bone is known to be a complication of ch...

Authors: Hiromitsu Hatakeyama, Noriyuki Fujima, Kazuhiko Tsuchiya, Kenji Mizoguchi, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma and Satoshi Fukuda

Subclinical focal cholangitis mimicking liver metastasis in asymptomatic patients with history of pancreatic ductal adenocarcinoma and biliary tree intervention

Cholangitis is an inflammatory process of the biliary tract with a wide range of clinical manifestations and it is not always considered in the differential diagnosis in asymptomatic patients. To the best of o...

Authors: Natally Horvat, Edmund M. Godfrey, Timothy J. Sadler, Jaclyn F. Hechtman, Laura H. Tang, Carlie S. Sigel, Serena Monti and Lorenzo Mannelli

Primary hepatic neuroendocrine tumors: multi-modal imaging features with pathological correlations

Primary hepatic neuroendocrine carcinomas (PHNECs) are rare and asymptomatic, and are therefore difficult to distinguish radiologically from other liver carcinomas. In this study, we aimed to determine the com...

Authors: Kai Yang, Ying-Sheng Cheng, Ji-Jin Yang, Xu Jiang and Ji-Xiang Guo

Imaging characteristics of cardiac metastases in patients with malignant melanoma

Due to prolonged survival and technical advances in CT imaging, cardiac metastases in patients with malignant melanoma are observed more frequently nowadays. The aim of the present study was to assess the anat...

Authors: Tanja Zitzelsberger, Thomas K. Eigentler, Patrick Krumm, Konstantin Nikolaou, Claus Garbe, Meinrad Gawaz and Bernhard Klumpp

Multiparametric imaging for detection and characterization of hepatocellular carcinoma using gadoxetic acid-enhanced MRI and perfusion-CT: which parameters work best?

MRI and perfusion-CT (PCT) are both useful imaging techniques for detection and characterization of liver lesions. The aim of this study was to compare the diagnostic accuracy of imaging parameters derived fro...

Authors: Mustafa Kurucay, Christopher Kloth, Sascha Kaufmann, Konstantin Nikolaou, Hans Bösmüller, Marius Horger and Wolfgang M. Thaiss

CT findings in patients with Cabazitaxel induced pelvic pain and haematuria: a case series

Haematuria and pelvic pain are recognized and documented adverse reactions related to Cabazitaxel use. To date there has not been any documentation of imaging findings in patients with this presentation.

Authors: Geethal N. Malalagama, Steve Chryssidis and Francis X Parnis

Incremental diagnostic utility of systematic double-bed SPECT/CT for bone scintigraphy in initial staging of cancer patients

SPECT/CT has been shown to increase the diagnostic performance of bone scintigraphy for staging of malignancies. A systematic double-bed SPECT/CT of the trunk may allow further improvement. However, this would...

Authors: Catherine Guezennec, Nathalie Keromnes, Philippe Robin, Ronan Abgral, David Bourhis, Solène Querellou, Romain de Laroche, Alexandra Le Duc-Pennec, Pierre-Yves Salaün and Pierre-Yves Le Roux

Additional value of ¹⁸F-FDG PET/CT response evaluation in axillary nodes during neoadjuvant therapy for triple-negative and HER2-positive breast cancer

¹⁸F-FDG PET/CT can monitor metabolic activity in early breast cancer during neoadjuvant systemic therapy (NST), but it is unknown if the metabolic breast and axillary response differ. ...

Authors: Mette S. van Ramshorst, Suzana C. Teixeira, Bas B. Koolen, Kenneth E. Pengel, Kenneth G. Gilhuijs, Jelle Wesseling, Sjoerd Rodenhuis, Renato A. Valdés Olmos, Emiel J. Rutgers, Wouter V. Vogel, Gabe S. Sonke and Marie-Jeanne T. Vrancken Peeters

Review of radiological classifications of pancreatic cancer with peripancreatic vessel invasion: are new grading criteria required?

Pancreatic cancer is mainly diagnosed at an advanced stage when adjacent vessel invasion is present; however, radical resection is potentially curative for selected patients with adjacent vessel invasion. Ther...

Authors: Y. N. Shen, X. L. Bai, G. G. Li and T. B. Liang

Effect of region of interest size on ADC measurements in pancreatic adenocarcinoma

To investigate the influence of region of interest (ROI) size on tumor apparent diffusion coefficient (ADC) measurements in pancreatic cancer.

Authors: Chao Ma, Xiaoyu Guo, Li Liu, Qian Zhan, Jing Li, Chengcheng Zhu, Li Wang, Jing Zhang, Xu Fang, Jianxun Qu, Shiyue Chen, Chengwei Shao and Jian-ping Lu

Intravoxel incoherent motion DWI of the pancreatic adenocarcinomas: monoexponential and biexponential apparent diffusion parameters and histopathological correlations

To investigate the associations between the diffusion parameters obtained from multiple-b-values diffusion weighted imaging (DWI) of pancreatic ductal adenocarcinoma (PDAC) and the aggressiveness and local sta...

Authors: Chao Ma, Yanjun Li, Li Wang, Yang Wang, Yong Zhang, He Wang, Shiyue Chen and Jianping Lu

Reproducibility and repeatability of same-day two sequential FDG PET/MR and PET/CT

To determine PET/CT and PET/MR reproducibility and PET/MR repeatability of fluorine 18 fluorodeoxyglucose (FDG) uptake measurements in tumors in cancer patients.

Authors: David Groshar, Hanna Bernstine, Natalia Goldberg, Meital Nidam, Dan Stein, Ifat Abadi-Korek and Liran Domachevsky

Evaluation of metabolic response with ¹⁸F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors

Patients with advanced or recurrent thymic epithelial tumors (TETs) often need several consecutive lines of chemotherapy. The aim of this retrospective monocentric study was to test whether ¹⁸F-Fluorodeoxyglucose...

Authors: Sabrina Segreto, Rosa Fonti, Margaret Ottaviano, Sara Pellegrino, Leonardo Pace, Vincenzo Damiano, Giovannella Palmieri and Silvana Del Vecchio