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  1. Accurate segmentation of head and neck squamous cell cancer (HNSCC) is important for radiotherapy treatment planning. Manual segmentation of these tumors is time-consuming and vulnerable to inconsistencies bet...

    Authors: Jens P.E. Schouten, Samantha Noteboom, Roland M. Martens, Steven W. Mes, C. René Leemans, Pim de Graaf and Martijn D. Steenwijk

    Citation: Cancer Imaging 2022 22:8

    Content type: Research article

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  2. The delayed percentage attenuation ratio (DPAR) was recently identified as a novel predictor of an early complete response in patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoemboliza...

    Authors: Lukas Müller, Felix Hahn, Florian Jungmann, Aline Mähringer-Kunz, Fabian Stoehr, Moritz C. Halfmann, Daniel Pinto dos Santos, Jan Hinrichs, Timo A. Auer, Christoph Düber and Roman Kloeckner

    Citation: Cancer Imaging 2022 22:5

    Content type: Research article

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  3. To develop and validate a radiomics nomogram for the preoperative prediction of lymph node (LN) metastasis in pancreatic ductal adenocarcinoma (PDAC).

    Authors: Yun Bian, Shiwei Guo, Hui Jiang, Suizhi Gao, Chengwei Shao, Kai Cao, Xu Fang, Jing Li, Li Wang, Chao Ma, Jianming Zheng, Gang Jin and Jianping Lu

    Citation: Cancer Imaging 2022 22:4

    Content type: Research article

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  4. 18F-FDG PET/CT plays an increasingly pivotal role in the staging and post-treatment monitoring of high-risk melanoma patients, augmented by the introduction of therapies, including tyrosine kinase inhibitors (TK....

    Authors: Nicolas Aide, Amir Iravani, Kevin Prigent, Diane Kottler, Ramin Alipour and Rodney J. Hicks

    Citation: Cancer Imaging 2022 22:3

    Content type: Review

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  5. Recent studies have suggested that periportal location of percutaneous radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is considered as one of the independent risk factors for local tumor prog...

    Authors: Shoujin Cao, Tianshi Lyu, Zeyang Fan, Haitao Guan, Li Song, Xiaoqiang Tong, Jian Wang and Yinghua Zou

    Citation: Cancer Imaging 2022 22:2

    Content type: Research article

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  6. The aim of this study was to explore the relationship between follow-up imaging characteristics and overall survival (OS) in advanced hepatocellular carcinoma (HCC) patients under sorafenib treatment.

    Authors: Osman Öcal, Regina Schinner, Kerstin Schütte, Enrico N. de Toni, Christian Loewe, Otto van Delden, Vincent Vandecaveye, Bernhard Gebauer, Christoph J. Zech, Christian Sengel, Irene Bargellini, Antonio Gasbarrini, Bruno Sangro, Maciej Pech, Peter Malfertheiner, Jens Ricke…

    Citation: Cancer Imaging 2022 22:1

    Content type: Research article

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  7. To determine whether the pulmonary MR imaging with free-breathing radial 3D fat-suppressed T1-weighted gradient echo (r-VIBE) sequence can detect lung lesions and display lesion profiles with an accuracy compa...

    Authors: Nan Yu, Haifeng Duan, Chuangbo Yang, Yong Yu and Shan Dang

    Citation: Cancer Imaging 2021 21:68

    Content type: Research article

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  8. Diffusion weighted imaging (DWI) with intravoxel incoherent motion (IVIM) modelling can inform on tissue perfusion without exogenous contrast administration. Dynamic-contrast-enhanced (DCE) MRI can also charac...

    Authors: Mihaela Rata, Khurum Khan, David J Collins, Dow-Mu Koh, Nina Tunariu, Maria Antonietta Bali, James d’Arcy, Jessica M Winfield, Simona Picchia, Nicola Valeri, Ian Chau, David Cunningham, Matteo Fassan, Martin O Leach and Matthew R Orton

    Citation: Cancer Imaging 2021 21:67

    Content type: Research article

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  9. The indication for endoscopic resection for submucosally invasive colorectal cancer (T1-CRC) depends on the preoperative diagnosis of invasion depth. The aim of this investigation was to evaluate the associati...

    Authors: Keisuke Kawasaki, Takehiro Torisu, Takahisa Nagahata, Motohiro Esaki, Koichi Kurahara, Makoto Eizuka, Yoshihito Tanaka, Minako Fujiwara, Shinichiro Kawatoko, Yumi Oshiro, Shun Yamada, Koji Ikegami, Shin Fujioka, Yuta Fuyuno, Yuichi Matsuno, Junji Umeno…

    Citation: Cancer Imaging 2021 21:66

    Content type: Research article

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  10. The Ki67 expression is associated with the advanced clinicopathological features and poor prognosis in bladder cancer (BCa). We aimed to develop and validate magnetic resonance imaging (MRI)-based radiomics si...

    Authors: Zongtai Zheng, Zhuoran Gu, Feijia Xu, Niraj Maskey, Yanyan He, Yang Yan, Tianyuan Xu, Shenghua Liu and Xudong Yao

    Citation: Cancer Imaging 2021 21:65

    Content type: Research article

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  11. Whole body DWI (WB-DWI) enables the identification of lymph nodes for disease evaluation. However, quantitative data of benign lymph nodes across the body are lacking to allow meaningful comparison of diseased...

    Authors: Ricardo Donners, Raphael Shih Zhu Yiin, Matthew Blackledge and Dow-Mu Koh

    Citation: Cancer Imaging 2021 21:64

    Content type: Research article

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  12. Structured reporting and standardized criteria are increasingly recognized as means of improving both radiological and clinical practice by allowing for better content and clarity. Our aim was to examine oncol...

    Authors: Elisabeta Valeria Spînu-Popa, Dania Cioni and Emanuele Neri

    Citation: Cancer Imaging 2021 21:63

    Content type: Research article

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  13. Indices obtained from lymph node dissection specimens, specifically lymph node yield (LNY) and lymph node ratio (LNR), have prognostic significance in the setting of head and neck squamous cell carcinoma (HNSC...

    Authors: Christiaan A. Rees, Joshua H. Litchman, Xiaotian Wu, Mariah M. Servos, Darcy A. Kerr, Ryan J. Halter, David A. Pastel and Joseph A. Paydarfar

    Citation: Cancer Imaging 2021 21:61

    Content type: Research article

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  14. The present study used dynamic-contrast enhanced MRI (DCE-MRI) to elucidate possible associations with tumor-infiltrating lymphocytes (TIL), stroma ratio and vimentin expression in head and neck squamous cell ...

    Authors: Hans-Jonas Meyer, Anne Kathrin Höhn and Alexey Surov

    Citation: Cancer Imaging 2021 21:60

    Content type: Research article

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  15. Functional MRI (fMRI) parameters analysis has been proven to be a promising tool of predicting therapeutic response to induction chemotherapy (IC) in nasopharyngeal carcinoma (NPC). The study was designed to iden...

    Authors: Da-wei Zhao, Wen-jun Fan, Ling-ling Meng, Yan-rong Luo, Jian Wei, Kun Liu, Gang Liu, Jin-feng Li, Xiao Zang, Meng Li, Xin-xin Zhang and Lin Ma

    Citation: Cancer Imaging 2021 21:59

    Content type: Research article

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  16. Imaging findings have a prominent role in early and correct identification of ovarian dysgerminoma, the most common ovarian malignant germ cell tumor (OMGCT). Despite Computed Tomography (CT) is widely used, M...

    Authors: Laura Maria Cacioppa, Federico Crusco, Francesco Marchetti, Michele Duranti, Matteo Renzulli and Rita Golfieri

    Citation: Cancer Imaging 2021 21:58

    Content type: Case series

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  17. The role of FDG-PET/CT imaging in assessing response to immunotherapy in advanced cutaneous squamous cell carcinoma (CSCC) is unknown. This study compared complete metabolic response (CMR) rates by FDG-PET and...

    Authors: Luke S. McLean, Karda Cavanagh, Rodney J. Hicks, Jason Callahan, Jing Xie, Anthony Cardin, Annette M. Lim and Danny Rischin

    Citation: Cancer Imaging 2021 21:57

    Content type: Research article

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  18. The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiologic...

    Authors: Shu-Cheng Liu, Jesyin Lai, Jhao-Yu Huang, Chia-Fong Cho, Pei Hua Lee, Min-Hsuan Lu, Chun-Chieh Yeh, Jiaxin Yu and Wei-Ching Lin

    Citation: Cancer Imaging 2021 21:56

    Content type: Research article

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  19. The aim of this study was to investigate the effect of combining immunohistochemical profiles and metabolic information to characterize breast cancer subtypes.

    Authors: Hyun Woo Kwon, Jeong Hyeon Lee, Kisoo Pahk, Kyong Hwa Park and Sungeun Kim

    Citation: Cancer Imaging 2021 21:55

    Content type: Research article

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  20. To explore the usefulness of analyzing histograms and textures of apparent diffusion coefficient (ADC) maps and T2-weighted (T2W) images to differentiate prostatic cancer (PCa) from benign prostatic hyperplasi...

    Authors: Pengyi Xing, Luguang Chen, Qingsong Yang, Tao Song, Chao Ma, Robert Grimm, Caixia Fu, Tiegong Wang, Wenjia Peng and Jianping Lu

    Citation: Cancer Imaging 2021 21:54

    Content type: Research article

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  21. Cystic renal cell carcinoma (CRCC) and cystic collecting duct carcinoma (CCDC) share similar oncogeni and some imaging findings. The aim of this study was to characterize the clinical and CT imagings features ...

    Authors: Qingqiang Zhu, Jun Ling, Jing Ye, Wenrong Zhu, Jingtao Wu and Wenxin Chen

    Citation: Cancer Imaging 2021 21:52

    Content type: Research article

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  22. To assess the spectrum and frequency of modalities used for emergency room (ER) imaging and their findings in pediatric cancer patients and assess their relationship with survival.

    Authors: Sungmin Woo, Abdallah Araji, Mohammad Ali El Amine, Natalie Gangai, Elizabeth Acquafredda, Anita P. Price, Tanya M. Trippett, Hedvig Hricak, Hebert Alberto Vargas and Gerald G. Behr

    Citation: Cancer Imaging 2021 21:51

    Content type: Research article

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  23. Preoperative evaluation of aggressiveness, including tumor histological subtype, grade of differentiation, Federation International of Gynecology and Obstetrics (FIGO) stage, and depth of myometrial invasion, ...

    Authors: Linqi Zhang, Xi Long, Mayidili Nijiati, Tianhui Zhang, Mengsi Li, Ying Deng, Sichi Kuang, Yuanqiang Xiao, Jie Zhu, Bingjun He, Jingbiao Chen, Phillip Rossman, Kevin J Glaser, Sudhakar K Venkatesh, Richard L Ehman and Jin Wang

    Citation: Cancer Imaging 2021 21:50

    Content type: Research article

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  24. To evaluate the application of Arterial Enhancement Fraction (AEF) texture features in predicting the tumor response in Hepatocellular Carcinoma (HCC) treated with Transarterial Chemoembolization (TACE) by mea...

    Authors: Xiaonan Mao, Yan Guo, Feng Wen, Hongyuan Liang, Wei Sun and Zaiming Lu

    Citation: Cancer Imaging 2021 21:49

    Content type: Research article

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  25. Tumor thickness and tumor volume measured by computed tomography (CT) were suggested as valuable prognosticator for patients’ survival diagnosed with malignant pleural mesothelioma (MPM). The purpose was to as...

    Authors: Olivia Lauk, Miriam Patella, Thomas Neuer, Bianca Battilana, Thomas Frauenfelder, Thi Dan Linh Nguyen-Kim, Walter Weder, Claudio Caviezel, Sven Hillinger, Ilhan Inci and Isabelle Opitz

    Citation: Cancer Imaging 2021 21:48

    Content type: Research article

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  26. To investigate the value of using specific region of interest (ROI) on contrast-enhanced CT for differentiating renal angiomyolipoma without visible fat (AML.wovf) from small clear cell renal cell carcinoma (c...

    Authors: Xu Wang, Ge Song and Haitao Jiang

    Citation: Cancer Imaging 2021 21:47

    Content type: Research article

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  27. To investigate the performance of magnetic resonance imaging (MRI)-based radiomics models for benign and malignant prostate lesion discrimination and extracapsular extension (ECE) and positive surgical margins...

    Authors: Dong He, Ximing Wang, Chenchao Fu, Xuedong Wei, Jie Bao, Xuefu Ji, Honglin Bai, Wei Xia, Xin Gao, Yuhua Huang and Jianquan Hou

    Citation: Cancer Imaging 2021 21:46

    Content type: Research article

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  28. To evaluate gadoxetic acid-enhanced liver MRI (EOB-MRI) versus contrast-enhanced computed tomography (CECT) for preoperative detection of liver metastasis (LM) and reduction of open-close laparotomies for panc...

    Authors: Kartik S. Jhaveri, Ali Babaei Jandaghi, Seng Thipphavong, Osvaldo Espin-Garcia, Anna Dodd, Shawn Hutchinson, Trevor W. Reichman, Carol-Anne Moulton, Ian D. McGilvary and Steven Gallinger

    Citation: Cancer Imaging 2021 21:45

    Content type: Research article

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  29. Performing Response Evaluation Criteria in Solid Tumor (RECISTS) measurement is a non-trivial task requiring much expertise and time. A deep learning-based algorithm has the potential to assist with rapid and ...

    Authors: MinJae Woo, A. Michael Devane, Steven C. Lowe, Ervin L Lowther and Ronald W. Gimbel

    Citation: Cancer Imaging 2021 21:43

    Content type: Research article

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  30. This study aimed to explore the spatial distribution of brain metastases (BMs) from small cell lung cancer (SCLC) a homogenous sample, and to identify the metastatic risk levels in brain regions.

    Authors: Yong Wang, Wei Xia, Baoyan Liu, Liu Zhou, Meng Ni, Rui Zhang, Jingyi Shen, Yujun Bai, Guixiang Weng, Shuanghu Yuan and Xin Gao

    Citation: Cancer Imaging 2021 21:41

    Content type: Research article

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  31. To establish and validate a high-resolution magnetic resonance imaging (HRMRI)-based radiomic nomogram for prediction of preoperative perineural invasion (PNI) of rectal cancer (RC).

    Authors: Yan-song Yang, Yong-juan Qiu, Gui-hua Zheng, Hai-peng Gong, Ya-qiong Ge, Yi-fei Zhang, Feng Feng and Yue-tao Wang

    Citation: Cancer Imaging 2021 21:40

    Content type: Research article

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  32. Neurolymphomatosis involving the cranial nerves (CNs) is rare. We sought a better understanding of the primary disease sites and patterns of spread in neurolymphomatosis of the orbit and retro-orbital cranial ...

    Authors: Seth J. Fritzhand, Bita Esmaeli, Jia Sun and J. Matthew Debnam

    Citation: Cancer Imaging 2021 21:39

    Content type: Research article

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  33. Early recurrence of oesophageal squamous cell carcinoma (SCC) is defined as recurrence after surgery within 1 year, and appears as local recurrence, distant recurrence, and lymph node positive and disseminated...

    Authors: Sun Tang, Jing Ou, Jun Liu, Yu-ping Wu, Chang-qiang Wu, Tian-wu Chen, Xiao-ming Zhang, Rui Li, Meng-jie Tang, Li-qin Yang, Bang-guo Tan, Fu-lin Lu and Jiani Hu

    Citation: Cancer Imaging 2021 21:38

    Content type: Research article

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  34. Most MRI radiomics studies to date, even multi-centre ones, have used “pure” datasets deliberately accrued from single-vendor, single-field-strength scanners. This does not reflect aspirations for the ultimate...

    Authors: Simon J. Doran, Santosh Kumar, Matthew Orton, James d’Arcy, Fenna Kwaks, Elizabeth O’Flynn, Zaki Ahmed, Kate Downey, Mitch Dowsett, Nicholas Turner, Christina Messiou and Dow-Mu Koh

    Citation: Cancer Imaging 2021 21:37

    Content type: Research article

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  35. Diagnostic and treatment response criteria for the JAK2/CALR/MPL mutation-related myeloproliferative neoplasms (MPNs) are largely based on bone marrow (BM) biopsy results. However, these biopsies have several ...

    Authors: Stefanie Slot, Niels W. C. J. van de Donk, René H. J. Otten, Bouke J. H. Boden, Josée Zijlstra, Pieter G. H. M. Raijmakers and Sonja Zweegman

    Citation: Cancer Imaging 2021 21:36

    Content type: Research article

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  36. Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing 68Ga -PSMA-11 and in 96.9% of patients undergoing 18F-DCFPyL PET/CT examination. We have observed ...

    Authors: Medhat M. Osman, Amir Iravani, Michael S. Hofman and Rodney J. Hicks

    Citation: Cancer Imaging 2021 21:35

    Content type: Case series

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  37. The extent of peritoneal carcinomatosis is difficult to estimate preoperatively, but a valid measure would be important in identifying operable patients.

    Authors: Björg Jónsdóttir, Montserrat Alemany Ripoll, Antonina Bergman, Ilvars Silins, Inger Sundström Poromaa, Håkan Ahlström and Karin Stålberg

    Citation: Cancer Imaging 2021 21:34

    Content type: Research article

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  38. Medullary thyroid cancer (MTC) has more aggressive behavior and poor prognosis. Ultrasound (US) has facilitated the qualitative diagnosis of thyroid nodules, however, some MTC may be diagnosed as a benign nodu...

    Authors: Jingzhu Zhao, Xiangqian Zheng, Ming Gao, Sheng Zhang, Xinwei Yun, Jiadong Chi and Guangwei Xu

    Citation: Cancer Imaging 2021 21:33

    Content type: Research article

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  39. To compare integrated slice-specific dynamic shimming (iShim) diffusion weighted imaging (DWI) and single-shot echo-planar imaging (SS-EPI) DWI in image quality and pathological characterization of rectal cancer.

    Authors: Jianxing Qiu, Jing Liu, Zhongxu Bi, Xiaowei Sun, Xin Wang, Junling Zhang, Chengwen Liu, Jinxia Zhu and Naishan Qin

    Citation: Cancer Imaging 2021 21:32

    Content type: Research article

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  40. Many studies have successfully identified radiomics features reflecting macroscale tumor features and tumor microenvironment for various organs. There is an increased interest in applying these radiomics featu...

    Authors: Seung-Hak Lee, Hwan-ho Cho, Junmo Kwon, Ho Yun Lee and Hyunjin Park

    Citation: Cancer Imaging 2021 21:31

    Content type: Research article

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  41. To probe the feasibility and reproducibility of diffusion kurtosis tensor imaging (DKTI) in renal cell carcinoma (RCC) and to apply DKTI in distinguishing the subtypes of RCC and the grades of clear cell RCC (...

    Authors: Jie Zhu, Xiaojie Luo, Jiayin Gao, Saying Li, Chunmei Li and Min Chen

    Citation: Cancer Imaging 2021 21:30

    Content type: Research article

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  42. The purpose of this study was to determine the potential value of magnetic resonance imaging (MRI) texture analysis (TA) in differentiating between benign and borderline/malignant phyllodes tumors of the breast.

    Authors: Xiaoguang Li, Nianping Jiang, Chunlai Zhang, Xiangguo Luo, Peng Zhong and Jingqin Fang

    Citation: Cancer Imaging 2021 21:29

    Content type: Research article

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  43. This study aimed to explore the sentinel lymph node (SLN) identification rate in breast cancer by subcutaneous and intradermal injection of ultrasound contrast agent in the mammary areola region, compared to t...

    Authors: Jun Luo, Liting Feng, Qing Zhou, Qin Chen, Jinping Liu, Chihua Wu, Jing Luo, Jie Chen, Hao Wu and Wanyue Deng

    Citation: Cancer Imaging 2021 21:28

    Content type: Research article

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  44. The purpose of this study was to develop a voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (P...

    Authors: Hiroyuki Tatekawa, Akifumi Hagiwara, Hiroyuki Uetani, Shadfar Bahri, Catalina Raymond, Albert Lai, Timothy F. Cloughesy, Phioanh L. Nghiemphu, Linda M. Liau, Whitney B. Pope, Noriko Salamon and Benjamin M. Ellingson

    Citation: Cancer Imaging 2021 21:27

    Content type: Research article

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