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  1. The role of FDG-PET/CT imaging in assessing response to immunotherapy in advanced cutaneous squamous cell carcinoma (CSCC) is unknown. This study compared complete metabolic response (CMR) rates by FDG-PET and...

    Authors: Luke S. McLean, Karda Cavanagh, Rodney J. Hicks, Jason Callahan, Jing Xie, Anthony Cardin, Annette M. Lim and Danny Rischin

    Citation: Cancer Imaging 2021 21:57

    Content type: Research article

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  2. The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiologic...

    Authors: Shu-Cheng Liu, Jesyin Lai, Jhao-Yu Huang, Chia-Fong Cho, Pei Hua Lee, Min-Hsuan Lu, Chun-Chieh Yeh, Jiaxin Yu and Wei-Ching Lin

    Citation: Cancer Imaging 2021 21:56

    Content type: Research article

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  3. The aim of this study was to investigate the effect of combining immunohistochemical profiles and metabolic information to characterize breast cancer subtypes.

    Authors: Hyun Woo Kwon, Jeong Hyeon Lee, Kisoo Pahk, Kyong Hwa Park and Sungeun Kim

    Citation: Cancer Imaging 2021 21:55

    Content type: Research article

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  4. To explore the usefulness of analyzing histograms and textures of apparent diffusion coefficient (ADC) maps and T2-weighted (T2W) images to differentiate prostatic cancer (PCa) from benign prostatic hyperplasi...

    Authors: Pengyi Xing, Luguang Chen, Qingsong Yang, Tao Song, Chao Ma, Robert Grimm, Caixia Fu, Tiegong Wang, Wenjia Peng and Jianping Lu

    Citation: Cancer Imaging 2021 21:54

    Content type: Research article

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  5. Cystic renal cell carcinoma (CRCC) and cystic collecting duct carcinoma (CCDC) share similar oncogeni and some imaging findings. The aim of this study was to characterize the clinical and CT imagings features ...

    Authors: Qingqiang Zhu, Jun Ling, Jing Ye, Wenrong Zhu, Jingtao Wu and Wenxin Chen

    Citation: Cancer Imaging 2021 21:52

    Content type: Research article

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  6. To assess the spectrum and frequency of modalities used for emergency room (ER) imaging and their findings in pediatric cancer patients and assess their relationship with survival.

    Authors: Sungmin Woo, Abdallah Araji, Mohammad Ali El Amine, Natalie Gangai, Elizabeth Acquafredda, Anita P. Price, Tanya M. Trippett, Hedvig Hricak, Hebert Alberto Vargas and Gerald G. Behr

    Citation: Cancer Imaging 2021 21:51

    Content type: Research article

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  7. Preoperative evaluation of aggressiveness, including tumor histological subtype, grade of differentiation, Federation International of Gynecology and Obstetrics (FIGO) stage, and depth of myometrial invasion, ...

    Authors: Linqi Zhang, Xi Long, Mayidili Nijiati, Tianhui Zhang, Mengsi Li, Ying Deng, Sichi Kuang, Yuanqiang Xiao, Jie Zhu, Bingjun He, Jingbiao Chen, Phillip Rossman, Kevin J Glaser, Sudhakar K Venkatesh, Richard L Ehman and Jin Wang

    Citation: Cancer Imaging 2021 21:50

    Content type: Research article

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  8. To evaluate the application of Arterial Enhancement Fraction (AEF) texture features in predicting the tumor response in Hepatocellular Carcinoma (HCC) treated with Transarterial Chemoembolization (TACE) by mea...

    Authors: Xiaonan Mao, Yan Guo, Feng Wen, Hongyuan Liang, Wei Sun and Zaiming Lu

    Citation: Cancer Imaging 2021 21:49

    Content type: Research article

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  9. Tumor thickness and tumor volume measured by computed tomography (CT) were suggested as valuable prognosticator for patients’ survival diagnosed with malignant pleural mesothelioma (MPM). The purpose was to as...

    Authors: Olivia Lauk, Miriam Patella, Thomas Neuer, Bianca Battilana, Thomas Frauenfelder, Thi Dan Linh Nguyen-Kim, Walter Weder, Claudio Caviezel, Sven Hillinger, Ilhan Inci and Isabelle Opitz

    Citation: Cancer Imaging 2021 21:48

    Content type: Research article

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  10. To investigate the value of using specific region of interest (ROI) on contrast-enhanced CT for differentiating renal angiomyolipoma without visible fat (AML.wovf) from small clear cell renal cell carcinoma (c...

    Authors: Xu Wang, Ge Song and Haitao Jiang

    Citation: Cancer Imaging 2021 21:47

    Content type: Research article

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  11. To investigate the performance of magnetic resonance imaging (MRI)-based radiomics models for benign and malignant prostate lesion discrimination and extracapsular extension (ECE) and positive surgical margins...

    Authors: Dong He, Ximing Wang, Chenchao Fu, Xuedong Wei, Jie Bao, Xuefu Ji, Honglin Bai, Wei Xia, Xin Gao, Yuhua Huang and Jianquan Hou

    Citation: Cancer Imaging 2021 21:46

    Content type: Research article

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  12. To evaluate gadoxetic acid-enhanced liver MRI (EOB-MRI) versus contrast-enhanced computed tomography (CECT) for preoperative detection of liver metastasis (LM) and reduction of open-close laparotomies for panc...

    Authors: Kartik S. Jhaveri, Ali Babaei Jandaghi, Seng Thipphavong, Osvaldo Espin-Garcia, Anna Dodd, Shawn Hutchinson, Trevor W. Reichman, Carol-Anne Moulton, Ian D. McGilvary and Steven Gallinger

    Citation: Cancer Imaging 2021 21:45

    Content type: Research article

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  13. Performing Response Evaluation Criteria in Solid Tumor (RECISTS) measurement is a non-trivial task requiring much expertise and time. A deep learning-based algorithm has the potential to assist with rapid and ...

    Authors: MinJae Woo, A. Michael Devane, Steven C. Lowe, Ervin L Lowther and Ronald W. Gimbel

    Citation: Cancer Imaging 2021 21:43

    Content type: Research article

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  14. This study aimed to explore the spatial distribution of brain metastases (BMs) from small cell lung cancer (SCLC) a homogenous sample, and to identify the metastatic risk levels in brain regions.

    Authors: Yong Wang, Wei Xia, Baoyan Liu, Liu Zhou, Meng Ni, Rui Zhang, Jingyi Shen, Yujun Bai, Guixiang Weng, Shuanghu Yuan and Xin Gao

    Citation: Cancer Imaging 2021 21:41

    Content type: Research article

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  15. To establish and validate a high-resolution magnetic resonance imaging (HRMRI)-based radiomic nomogram for prediction of preoperative perineural invasion (PNI) of rectal cancer (RC).

    Authors: Yan-song Yang, Yong-juan Qiu, Gui-hua Zheng, Hai-peng Gong, Ya-qiong Ge, Yi-fei Zhang, Feng Feng and Yue-tao Wang

    Citation: Cancer Imaging 2021 21:40

    Content type: Research article

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  16. Neurolymphomatosis involving the cranial nerves (CNs) is rare. We sought a better understanding of the primary disease sites and patterns of spread in neurolymphomatosis of the orbit and retro-orbital cranial ...

    Authors: Seth J. Fritzhand, Bita Esmaeli, Jia Sun and J. Matthew Debnam

    Citation: Cancer Imaging 2021 21:39

    Content type: Research article

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  17. Early recurrence of oesophageal squamous cell carcinoma (SCC) is defined as recurrence after surgery within 1 year, and appears as local recurrence, distant recurrence, and lymph node positive and disseminated...

    Authors: Sun Tang, Jing Ou, Jun Liu, Yu-ping Wu, Chang-qiang Wu, Tian-wu Chen, Xiao-ming Zhang, Rui Li, Meng-jie Tang, Li-qin Yang, Bang-guo Tan, Fu-lin Lu and Jiani Hu

    Citation: Cancer Imaging 2021 21:38

    Content type: Research article

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  18. Most MRI radiomics studies to date, even multi-centre ones, have used “pure” datasets deliberately accrued from single-vendor, single-field-strength scanners. This does not reflect aspirations for the ultimate...

    Authors: Simon J. Doran, Santosh Kumar, Matthew Orton, James d’Arcy, Fenna Kwaks, Elizabeth O’Flynn, Zaki Ahmed, Kate Downey, Mitch Dowsett, Nicholas Turner, Christina Messiou and Dow-Mu Koh

    Citation: Cancer Imaging 2021 21:37

    Content type: Research article

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  19. Diagnostic and treatment response criteria for the JAK2/CALR/MPL mutation-related myeloproliferative neoplasms (MPNs) are largely based on bone marrow (BM) biopsy results. However, these biopsies have several ...

    Authors: Stefanie Slot, Niels W. C. J. van de Donk, René H. J. Otten, Bouke J. H. Boden, Josée Zijlstra, Pieter G. H. M. Raijmakers and Sonja Zweegman

    Citation: Cancer Imaging 2021 21:36

    Content type: Research article

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  20. Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing 68Ga -PSMA-11 and in 96.9% of patients undergoing 18F-DCFPyL PET/CT examination. We have observed ...

    Authors: Medhat M. Osman, Amir Iravani, Michael S. Hofman and Rodney J. Hicks

    Citation: Cancer Imaging 2021 21:35

    Content type: Case series

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  21. The extent of peritoneal carcinomatosis is difficult to estimate preoperatively, but a valid measure would be important in identifying operable patients.

    Authors: Björg Jónsdóttir, Montserrat Alemany Ripoll, Antonina Bergman, Ilvars Silins, Inger Sundström Poromaa, Håkan Ahlström and Karin Stålberg

    Citation: Cancer Imaging 2021 21:34

    Content type: Research article

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  22. Medullary thyroid cancer (MTC) has more aggressive behavior and poor prognosis. Ultrasound (US) has facilitated the qualitative diagnosis of thyroid nodules, however, some MTC may be diagnosed as a benign nodu...

    Authors: Jingzhu Zhao, Xiangqian Zheng, Ming Gao, Sheng Zhang, Xinwei Yun, Jiadong Chi and Guangwei Xu

    Citation: Cancer Imaging 2021 21:33

    Content type: Research article

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  23. To compare integrated slice-specific dynamic shimming (iShim) diffusion weighted imaging (DWI) and single-shot echo-planar imaging (SS-EPI) DWI in image quality and pathological characterization of rectal cancer.

    Authors: Jianxing Qiu, Jing Liu, Zhongxu Bi, Xiaowei Sun, Xin Wang, Junling Zhang, Chengwen Liu, Jinxia Zhu and Naishan Qin

    Citation: Cancer Imaging 2021 21:32

    Content type: Research article

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  24. Many studies have successfully identified radiomics features reflecting macroscale tumor features and tumor microenvironment for various organs. There is an increased interest in applying these radiomics featu...

    Authors: Seung-Hak Lee, Hwan-ho Cho, Junmo Kwon, Ho Yun Lee and Hyunjin Park

    Citation: Cancer Imaging 2021 21:31

    Content type: Research article

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  25. To probe the feasibility and reproducibility of diffusion kurtosis tensor imaging (DKTI) in renal cell carcinoma (RCC) and to apply DKTI in distinguishing the subtypes of RCC and the grades of clear cell RCC (...

    Authors: Jie Zhu, Xiaojie Luo, Jiayin Gao, Saying Li, Chunmei Li and Min Chen

    Citation: Cancer Imaging 2021 21:30

    Content type: Research article

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  26. The purpose of this study was to determine the potential value of magnetic resonance imaging (MRI) texture analysis (TA) in differentiating between benign and borderline/malignant phyllodes tumors of the breast.

    Authors: Xiaoguang Li, Nianping Jiang, Chunlai Zhang, Xiangguo Luo, Peng Zhong and Jingqin Fang

    Citation: Cancer Imaging 2021 21:29

    Content type: Research article

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  27. This study aimed to explore the sentinel lymph node (SLN) identification rate in breast cancer by subcutaneous and intradermal injection of ultrasound contrast agent in the mammary areola region, compared to t...

    Authors: Jun Luo, Liting Feng, Qing Zhou, Qin Chen, Jinping Liu, Chihua Wu, Jing Luo, Jie Chen, Hao Wu and Wanyue Deng

    Citation: Cancer Imaging 2021 21:28

    Content type: Research article

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  28. The purpose of this study was to develop a voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (P...

    Authors: Hiroyuki Tatekawa, Akifumi Hagiwara, Hiroyuki Uetani, Shadfar Bahri, Catalina Raymond, Albert Lai, Timothy F. Cloughesy, Phioanh L. Nghiemphu, Linda M. Liau, Whitney B. Pope, Noriko Salamon and Benjamin M. Ellingson

    Citation: Cancer Imaging 2021 21:27

    Content type: Research article

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  29. Accurate diagnosis of high-grade branching type intraductal papillary mucinous neoplasms (BD-IPMNs) is challenging in clinical setting. We aimed to construct and validate a nomogram combining clinical characte...

    Authors: Sijia Cui, Tianyu Tang, Qiuming Su, Yajie Wang, Zhenyu Shu, Wei Yang and Xiangyang Gong

    Citation: Cancer Imaging 2021 21:26

    Content type: Research article

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  30. Papillary renal cell carcinoma (RCC) is the second most common subtype of RCC, after clear cell RCC. This study aimed to investigate the usefulness of FDG PET/CT in primary and recurrent papillary RCC, and the...

    Authors: Guozhu Hou, Dachun Zhao, Yuanyuan Jiang, Zhaohui Zhu, Li Huo, Fang Li and Wuying Cheng

    Citation: Cancer Imaging 2021 21:25

    Content type: Research article

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  31. Fumarate hydratase-deficient renal cell carcinoma (FH-RCC) is a subtype of RCC that is increasingly recognized pathologically. The aim of this study was to evaluate the imaging features of FH-RCC on computed t...

    Authors: Ines Nikolovski, Maria I. Carlo, Ying-Bei Chen and Hebert Alberto Vargas

    Citation: Cancer Imaging 2021 21:24

    Content type: Research article

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  32. There is a paucity of existing literature centering on the magnetic resonance (MR) imaging features of pancreatic schwannomas, due to the neoplasm’s nonspecific presentation and its rarity. We aimed to identif...

    Authors: Zhenshan Shi, Dairong Cao, Qian Zhuang, Ruixiong You, Xiumei Li, Zhongmin Li, Yueming Li and Xinming Huang

    Citation: Cancer Imaging 2021 21:23

    Content type: Research article

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  33. Expression of CXCR4, a chemokine (C-X-C motif) receptor that plays a central role in tumor growth and metastasis of circulating tumor cells, has been described in a variety of solid tumors. A high expression o...

    Authors: Philipp Linde, Christian Baues, Simone Wegen, Maike Trommer, Alexander Quaas, Johannes Rosenbrock, Eren Celik, Simone Marnitz, Christiane J. Bruns, Thomas Fischer, Klaus Schomaecker, Hans-Juergen Wester, Alexander Drzezga, Lutz van Heek and Carsten Kobe

    Citation: Cancer Imaging 2021 21:22

    Content type: Research article

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  34. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Philippe Jagoda, Jochen Fleckenstein, Mathias Sonnhoff, Günther Schneider, Christian Ruebe, Arno Buecker and Jonas Stroeder

    Citation: Cancer Imaging 2021 21:21

    Content type: Correction

    Published on:

    The original article was published in Cancer Imaging 2021 21:15

  35. Radiomics is a promising field in oncology imaging. However, the implementation of radiomics clinically has been limited because its robustness remains unclear. Previous CT and PET studies suggested that radio...

    Authors: Shin-Hyung Park, Hyejin Lim, Bong Kyung Bae, Myong Hun Hahm, Gun Oh Chong, Shin Young Jeong and Jae-Chul Kim

    Citation: Cancer Imaging 2021 21:19

    Content type: Research article

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  36. The purpose of this study was to analyze if the use of texture analysis on spectral detector CT (SDCT)-derived iodine maps (IM) in addition to conventional images (CI) improves lung nodule differentiation, whe...

    Authors: Simon Lennartz, Alina Mager, Nils Große Hokamp, Sebastian Schäfer, David Zopfs, David Maintz, Hans Christian Reinhardt, Roman K. Thomas, Liliana Caldeira and Thorsten Persigehl

    Citation: Cancer Imaging 2021 21:17

    Content type: Research article

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  37. The use of PET/MRI for gynecological cancers is emerging. The purpose of this study was to assess the additional diagnostic value of PET over MRI alone in local and whole-body staging of cervical cancer, and t...

    Authors: Aida Steiner, Sara Narva, Irina Rinta-Kiikka, Sakari Hietanen, Johanna Hynninen and Johanna Virtanen

    Citation: Cancer Imaging 2021 21:16

    Content type: Research article

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  38. Computed tomography (CT) is the standard procedure for follow-up of non-small-cell lung cancer (NSCLC) after radiochemotherapy. CT has difficulties differentiating between tumor, atelectasis and radiation indu...

    Authors: Philippe Jagoda, Jochen Fleckenstein, Mathias Sonnhoff, Günther Schneider, Christian Ruebe, Arno Buecker and Jonas Stroeder

    Citation: Cancer Imaging 2021 21:15

    Content type: Research article

    Published on:

    The Correction to this article has been published in Cancer Imaging 2021 21:21

  39. Interstitial lung abnormalities (ILA) can be detected on computed tomography (CT) in lung cancer patients and have an association with mortality in advanced non-small cell lung cancer (NSCLC) patients. The aim...

    Authors: Tomoyuki Hida, Akinori Hata, Junwei Lu, Vladimir I. Valtchinov, Takuya Hino, Mizuki Nishino, Hiroshi Honda, Noriyuki Tomiyama, David C. Christiani and Hiroto Hatabu

    Citation: Cancer Imaging 2021 21:14

    Content type: Research article

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  40. The aim of this study was to compare intravoxel incoherent motion (IVIM) diffusion weighted (DW) MRI and CT perfusion to assess tumor perfusion of pancreatic ductal adenocarcinoma (PDAC).

    Authors: Philipp Mayer, Franziska Fritz, Marco Koell, Stephan Skornitzke, Frank Bergmann, Matthias M. Gaida, Thilo Hackert, Klaus Maier-Hein, Frederik B. Laun, Hans-Ulrich Kauczor, Lars Grenacher, Miriam Klauß and Wolfram Stiller

    Citation: Cancer Imaging 2021 21:13

    Content type: Research article

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  41. To compare different fitting methods for determining IVIM (Intravoxel Incoherent Motion) parameters and to determine whether the use of different IVIM fitting methods would affect differentiation of cervix can...

    Authors: Xue Wang, Jiao Song, Shengfa Zhou, Yi Lu, Wenxiao Lin, Tong San Koh, Zujun Hou and Zhihan Yan

    Citation: Cancer Imaging 2021 21:12

    Content type: Research article

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  42. The prognostic value of 18F-FDG PET/CT in extranodal natural killer/T-cell lymphoma (ENKTL) is not well established. We aimed to develop nomograms for individualized estimates of progression-free survival (PFS) a...

    Authors: Hongyan Li, Guozhu Shao, Yajing Zhang, Xiaomin Chen, Chengcheng Du, Kun Wang and Zairong Gao

    Citation: Cancer Imaging 2021 21:9

    Content type: Research article

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  43. In this study, we investigated the relationship between clinicopathologic factors, BRAFV600E mutation status and [18F] F-fluoro-2-deoxyglucose (FDG) avidity in patients with radioiodine (RAI)-negative recurrent o...

    Authors: Le Ngoc Ha, Amir Iravani, Nguyen Thi Nhung, Ngo Thi Minh Hanh, Febby Hutomo and Mai Hong Son

    Citation: Cancer Imaging 2021 21:8

    Content type: Research article

    Published on:

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