Articles

Imaging features of fibrolamellar hepatocellular carcinoma in gadoxetic acid-enhanced MRI

Fibrolamellar hepatocellular carcinoma (FLC) is a rare malignancy occurring in young patients without cirrhosis. Objectives of our study were to analyze contrast material uptake in hepatobiliary phase imaging ...

Authors: Viktoria Palm, Ruofan Sheng, Philipp Mayer, Karl-Heinz Weiss, Christoph Springfeld, Arianeb Mehrabi, Thomas Longerich, Anne Katrin Berger, Hans-Ulrich Kauczor and Tim Frederik Weber

MRI features of combined hepatocellular- cholangiocarcinoma versus mass forming intrahepatic cholangiocarcinoma

Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary liver tumor, which has overlapping imaging features with mass forming intra-hepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma ...

Authors: Jennifer Sammon, Sandra Fischer, Ravi Menezes, Hooman Hosseini-Nik, Sara Lewis, Bachir Taouli and Kartik Jhaveri

Primary carcinosarcoma of the liver: imaging features and clinical findings in six cases and a review of the literature

Carcinosarcoma of the liver is a very rare tumor composed of a mixture of carcinomatous and sarcomatous elements. Less than 25 adequately documented cases have been reported, with inadequate description of ima...

Authors: Jing Li, Pan Liang, Dandan Zhang, Jie Liu, Hongkai Zhang, Jinrong Qu and Jianbo Gao

RETRACTED ARTICLE: Pre-treatment DWI as a predictor of overall survival in locally advanced pancreatic cancer treated with Cyberknife radiotherapy and sequential S-1 therapy

To identify the value of the pre-treatment apparent diffusion coefficient (ADC) derived from diffusion weighted imaging (DWI) in predicting the overall survival (OS) for locally advanced pancreatic cancer (LAP...

Authors: Yu Zhang, Xiaofei Zhu, Denghui Liu, Jiaqi Song, Huojun Zhang and Jianping Lu

Cement pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients

Vertebroplasty is a minimally invasive procedure commonly performed for vertebral compression fractures secondary to osteoporosis or malignancy. Leakage of bone cement into the paravertebral venous system and ...

Authors: Asem Mansour, Nayef Abdel-Razeq, Hussein Abuali, Mohammad Makoseh, Nouran Shaikh-Salem, Kamelah Abushalha and Samer Salah

Diagnostic performance of ¹⁸F-FDG PET/CT using point spread function reconstruction on initial staging of rectal cancer: a comparison study with conventional PET/CT and pelvic MRI

Accurate staging is crucial for treatment selection and prognosis prediction in patients with rectal cancer. Point spread function (PSF) reconstruction can improve spatial resolution and signal-to-noise ratio ...

Authors: Masatoshi Hotta, Ryogo Minamimoto, Hideaki Yano, Yoshimasa Gohda and Yasutaka Shuno

Changes in biodistribution on ⁶⁸Ga-DOTA-Octreotate PET/CT after long acting somatostatin analogue therapy in neuroendocrine tumour patients may result in pseudoprogression

To evaluate the effects of long-acting somatostatin analogue (SSA) therapy on ⁶⁸Ga-DOTA-octreotate (GaTate) uptake at physiological and metastatic sites in neuroendocrine tumour (NET) patients.

Authors: Martin H. Cherk, Grace Kong, Rodney J. Hicks and Michael S. Hofman

¹⁸F–FDG-PET/CT and diffusion-weighted MRI for monitoring a BRAF and CDK 4/6 inhibitor combination therapy in a murine model of human melanoma

The purpose of the study was to investigate a novel BRAF and CDK 4/6 inhibitor combination therapy in a murine model of BRAF-V600-mutant human melanoma monitored by ¹⁸F–FDG-PET/CT and diffusion-weighted MRI (DW-M...

Authors: Ralf S. Eschbach, Philipp M. Kazmierczak, Maurice M. Heimer, Andrei Todica, Heidrun Hirner-Eppeneder, Moritz J. Schneider, Georg Keinrath, Olga Solyanik, Jessica Olivier, Wolfgang G. Kunz, Maximilian F. Reiser, Peter Bartenstein, Jens Ricke and Clemens C. Cyran

Identification of the pericardiacophrenic vein on CT

To evaluate the depictability of pericardiacophrenic veins (PCPV) as landmarks for the location of the phrenic nerves on multi-detector-row computed tomography (MDCT), and to investigate the usefulness of depi...

Authors: Yoshiyuki Ozawa, Ritsuko Suzuki, Masaki Hara and Yuta Shibamoto

⁶⁸Ga PSMA-11 PET with CT urography protocol in the initial staging and biochemical relapse of prostate cancer

⁶⁸Ga-labelled prostate specific membrane antigen (PSMA) ligand PET/CT is a promising modality in primary staging (PS) and biochemical relapse (BCR) of prostate cancer (PC). However, pe...

Authors: Amir Iravani, Michael S. Hofman, Tony Mulcahy, Scott Williams, Declan Murphy, Bimal K. Parameswaran and Rodney J. Hicks

Integration of CT urography improves diagnostic confidence of ⁶⁸Ga-PSMA-11 PET/CT in prostate cancer patients

To prove the feasibility of integrating CT urography (CTU) into ⁶⁸Ga-PSMA-11 PET/CT and to analyze the impact of CTU on assigning focal tracer accumulation in the ureteric space to either ureteric excretion or me...

Authors: Leon Will, Frederik L. Giesel, Martin T. Freitag, Anne K. Berger, Walter Mier, Klaus Kopka, Stefan A. Koerber, Hendrik Rathke, Christophe Kremer, Clemens Kratochwil, Hans-Ulrich Kauczor, Uwe Haberkorn and Tim F. Weber

3.0T MRI for long-term observation of lung nodules post cryoablation: a pilot study

The purpose of this study was to use serial magnetic resonance imaging (MRI) examinations to observe changes in malignant lung tumors over time post-cryoablation.

Authors: Jing Li, Jinrong Qu, Hongkai Zhang, Yingshu Wang, Lin Zheng, Xiang Geng, Yan Zhao and Hailiang Li

How we read pediatric PET/CT: indications and strategies for image acquisition, interpretation and reporting

PET/CT plays an important role in the diagnosis, staging and management of many pediatric malignancies. The techniques for performing PET/CT examinations in children have evolved, with increasing attention foc...

Authors: Gabrielle C. Colleran, Neha Kwatra, Leah Oberg, Frederick D. Grant, Laura Drubach, Michael J. Callahan, Robert D. MacDougall, Frederic H. Fahey and Stephan D. Voss

Comparison of efficacy and complications of endoscopic and percutaneous biliary drainage in malignant obstructive jaundice: a systematic review and meta-analysis

Malignant obstructive jaundice is a common problem in the clinic. Currently, the generally applied treatment methods are percutaneous transhepatic biliary drainage (PTBD) and endoscopic biliary drainage (EBD)....

Authors: Feng Duan, Li Cui, Yanhua Bai, Xiaohui Li, Jieyu Yan and Xuan Liu

Lymphomatosis cerebri: a rare variant of primary central nervous system lymphoma and MR imaging features

Lymphomatosis cerebri (LC) is a rare variant of primary central nervous system lymphoma (PCNSL), characterized by diffuse infiltration without the formation of a discrete mass. The diagnosis of LC is a challen...

Authors: Hui Yu, Bo Gao, Jing Liu, Yong-Cheng Yu, Mark S. Shiroishi, Ming-Ming Huang, Wen-Xiu Yang and Zhi-Zhong Guan

Portal vein embolization with n-butyl-cyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients

To evaluate the efficacy of portal vein embolization (PVE) with n-Butyl-cyanoacrylate (NBCA) through an ipsilateral approach before major hepatectomy. Secondary end-points were PVE safety, liver resection and ...

Authors: José Hugo Mendes Luz, Paula Mendes Luz, Tiago Bilhim, Henrique Salas Martin, Hugo Rodrigues Gouveia, Élia Coimbra, Filipe Veloso Gomes, Roberto Romulo Souza, Igor Murad Faria and Tiago Nepomuceno de Miranda

Proceedings of the International Cancer Imaging Society (ICIS) 17th Annual Teaching Course

Authors:

¹⁸F-FDG PET/CT response in a phase 1/2 trial of nab-paclitaxel plus gemcitabine for advanced pancreatic cancer

Positron emission tomography (PET) is poised to become a useful imaging modality in staging and evaluating therapeutic responses in patients with metastatic pancreatic cancer (mPC). This analysis from a phase ...

Authors: Ronald L. Korn, Daniel D. Von Hoff, Mitesh J. Borad, Markus F. Renschler, Desmond McGovern, R. Curtis Bay and Ramesh K. Ramanathan

Osteoradionecrosis of the hyoid bone after intra-arterial chemoradiotherapy for oropharyngeal cancer: MR imaging findings

Osteoradionecrosis (ORN) of the hyoid bone sometimes induces severe front neck infection and can cause laryngeal stenosis and carotid rupture. Although ORN of the hyoid bone is known to be a complication of ch...

Authors: Hiromitsu Hatakeyama, Noriyuki Fujima, Kazuhiko Tsuchiya, Kenji Mizoguchi, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma and Satoshi Fukuda

Subclinical focal cholangitis mimicking liver metastasis in asymptomatic patients with history of pancreatic ductal adenocarcinoma and biliary tree intervention

Cholangitis is an inflammatory process of the biliary tract with a wide range of clinical manifestations and it is not always considered in the differential diagnosis in asymptomatic patients. To the best of o...

Authors: Natally Horvat, Edmund M. Godfrey, Timothy J. Sadler, Jaclyn F. Hechtman, Laura H. Tang, Carlie S. Sigel, Serena Monti and Lorenzo Mannelli

Primary hepatic neuroendocrine tumors: multi-modal imaging features with pathological correlations

Primary hepatic neuroendocrine carcinomas (PHNECs) are rare and asymptomatic, and are therefore difficult to distinguish radiologically from other liver carcinomas. In this study, we aimed to determine the com...

Authors: Kai Yang, Ying-Sheng Cheng, Ji-Jin Yang, Xu Jiang and Ji-Xiang Guo

Imaging characteristics of cardiac metastases in patients with malignant melanoma

Due to prolonged survival and technical advances in CT imaging, cardiac metastases in patients with malignant melanoma are observed more frequently nowadays. The aim of the present study was to assess the anat...

Authors: Tanja Zitzelsberger, Thomas K. Eigentler, Patrick Krumm, Konstantin Nikolaou, Claus Garbe, Meinrad Gawaz and Bernhard Klumpp

Multiparametric imaging for detection and characterization of hepatocellular carcinoma using gadoxetic acid-enhanced MRI and perfusion-CT: which parameters work best?

MRI and perfusion-CT (PCT) are both useful imaging techniques for detection and characterization of liver lesions. The aim of this study was to compare the diagnostic accuracy of imaging parameters derived fro...

Authors: Mustafa Kurucay, Christopher Kloth, Sascha Kaufmann, Konstantin Nikolaou, Hans Bösmüller, Marius Horger and Wolfgang M. Thaiss

CT findings in patients with Cabazitaxel induced pelvic pain and haematuria: a case series

Haematuria and pelvic pain are recognized and documented adverse reactions related to Cabazitaxel use. To date there has not been any documentation of imaging findings in patients with this presentation.

Authors: Geethal N. Malalagama, Steve Chryssidis and Francis X Parnis

Incremental diagnostic utility of systematic double-bed SPECT/CT for bone scintigraphy in initial staging of cancer patients

SPECT/CT has been shown to increase the diagnostic performance of bone scintigraphy for staging of malignancies. A systematic double-bed SPECT/CT of the trunk may allow further improvement. However, this would...

Authors: Catherine Guezennec, Nathalie Keromnes, Philippe Robin, Ronan Abgral, David Bourhis, Solène Querellou, Romain de Laroche, Alexandra Le Duc-Pennec, Pierre-Yves Salaün and Pierre-Yves Le Roux

Additional value of ¹⁸F-FDG PET/CT response evaluation in axillary nodes during neoadjuvant therapy for triple-negative and HER2-positive breast cancer

¹⁸F-FDG PET/CT can monitor metabolic activity in early breast cancer during neoadjuvant systemic therapy (NST), but it is unknown if the metabolic breast and axillary response differ. ...

Authors: Mette S. van Ramshorst, Suzana C. Teixeira, Bas B. Koolen, Kenneth E. Pengel, Kenneth G. Gilhuijs, Jelle Wesseling, Sjoerd Rodenhuis, Renato A. Valdés Olmos, Emiel J. Rutgers, Wouter V. Vogel, Gabe S. Sonke and Marie-Jeanne T. Vrancken Peeters

Review of radiological classifications of pancreatic cancer with peripancreatic vessel invasion: are new grading criteria required?

Pancreatic cancer is mainly diagnosed at an advanced stage when adjacent vessel invasion is present; however, radical resection is potentially curative for selected patients with adjacent vessel invasion. Ther...

Authors: Y. N. Shen, X. L. Bai, G. G. Li and T. B. Liang

Effect of region of interest size on ADC measurements in pancreatic adenocarcinoma

To investigate the influence of region of interest (ROI) size on tumor apparent diffusion coefficient (ADC) measurements in pancreatic cancer.

Authors: Chao Ma, Xiaoyu Guo, Li Liu, Qian Zhan, Jing Li, Chengcheng Zhu, Li Wang, Jing Zhang, Xu Fang, Jianxun Qu, Shiyue Chen, Chengwei Shao and Jian-ping Lu

Intravoxel incoherent motion DWI of the pancreatic adenocarcinomas: monoexponential and biexponential apparent diffusion parameters and histopathological correlations

To investigate the associations between the diffusion parameters obtained from multiple-b-values diffusion weighted imaging (DWI) of pancreatic ductal adenocarcinoma (PDAC) and the aggressiveness and local sta...

Authors: Chao Ma, Yanjun Li, Li Wang, Yang Wang, Yong Zhang, He Wang, Shiyue Chen and Jianping Lu

Reproducibility and repeatability of same-day two sequential FDG PET/MR and PET/CT

To determine PET/CT and PET/MR reproducibility and PET/MR repeatability of fluorine 18 fluorodeoxyglucose (FDG) uptake measurements in tumors in cancer patients.

Authors: David Groshar, Hanna Bernstine, Natalia Goldberg, Meital Nidam, Dan Stein, Ifat Abadi-Korek and Liran Domachevsky

Evaluation of metabolic response with ¹⁸F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors

Patients with advanced or recurrent thymic epithelial tumors (TETs) often need several consecutive lines of chemotherapy. The aim of this retrospective monocentric study was to test whether ¹⁸F-Fluorodeoxyglucose...

Authors: Sabrina Segreto, Rosa Fonti, Margaret Ottaviano, Sara Pellegrino, Leonardo Pace, Vincenzo Damiano, Giovannella Palmieri and Silvana Del Vecchio

Imaging of hepatocellular carcinoma and image guided therapies - how we do it

Treatment options for hepatocellular carcinoma have evolved over recent years. Interventional radiologists and surgeons can offer curative treatments for early stage tumours, and locoregional therapies can be ...

Authors: Jonathon Willatt, Julie A. Ruma, Shadi F. Azar, Nara L. Dasika and F. Syed

The prognostic value of location and size change of pathological lymph nodes evaluated on CT-scan following radiotherapy in head and neck cancer

Overall survival after chemo-radiotherapy (CRT) for head and neck cancer ranges between 50 and 60% after 5 year of follow-up. Local and/or regional recurrence is the most frequent form of therapy failure. The ...

Authors: Daan Nevens, Olivier Vantomme, Annouschka Laenen, Robert Hermans and Sandra Nuyts

Crizotinib Associated Renal Cysts [CARCs]: incidence and patterns of evolution

Novel therapeutic agents recently introduced for the treatment of cancer have several unusual side effects. An increased incidence of renal cystic lesions, often with features concerning for malignancy or infe...

Authors: Laird B Cameron, Damian H S Jiang, Kate Moodie, Catherine Mitchell, Benjamin Solomon and Bimal Kumar Parameswaran

Whole-body MRI in pediatric patients with cancer

Cancer is the leading cause of natural death in the pediatric populations of developed countries, yet cure rates are greater than 70% when a cancer is diagnosed in its early stages. Recent advances in magnetic...

Authors: Marcos Duarte Guimarães, Julia Noschang, Sara Reis Teixeira, Marcel Koenigkam Santos, Henrique Manoel Lederman, Vivian Tostes, Vikas Kundra, Alex Dias Oliveira, Bruno Hochhegger and Edson Marchiori

DEB TACE for Intermediate and advanced HCC – Initial Experience in a Brazilian Cancer Center

According to Barcelona Clinic Liver Cancer classification transarterial chemoembolization is indicated in patients with Hepatocellular Carcinoma in the intermediate stage. Drug-eluting microspheres can absorb ...

Authors: Jose Hugo Mendes Luz, Paula M. Luz, Henrique S. Martin, Hugo R. Gouveia, Raphal Braz Levigard, Felipe Diniz Nogueira, Bernardo Caetano Rodrigues, Tiago Nepomuceno de Miranda and Marcelo Henrique Mamede

CT texture analysis: a potential tool for prediction of survival in patients with metastatic clear cell carcinoma treated with sunitinib

To assess CT texture based quantitative imaging biomarkers in the prediction of progression free survival (PFS) and overall survival (OS) in patients with clear cell renal cell carcinoma undergoing treatment w...

Authors: Masoom A. Haider, Alireza Vosough, Farzad Khalvati, Alexander Kiss, Balaji Ganeshan and Georg A. Bjarnason

Assessment and diagnostic accuracy of lymph node status to predict stage III colon cancer using computed tomography

To study different imaging criteria for prediction of lymph node metastases (Stage III disease) in colon cancer using CT.

Authors: Erik Rollvén, Mirna Abraham-Nordling, Torbjörn Holm and Lennart Blomqvist

Radioiodine sinus uptake related to mucosal thickening or aspergilloma: a case series of an unrecognized event well evidenced by SPECT/CT

False-positive radioiodine (RAI) uptake related to chronic sinusitis and mucocele has only rarely been reported in patients with differentiated thyroid cancer (DTC) even with the recent use of single photon em...

Authors: Renaud Ciappuccini, David Blanchard, Jean-Pierre Rame, Dominique de Raucourt, Emmanuel Babin and Stéphane Bardet

3D analysis of apparent diffusion coefficient histograms in hepatocellular carcinoma: correlation with histological grade

To evaluate the usefulness of differentiation of histological grade in hepatocellular carcinoma (HCC) using three-dimensional (3D) analysis of apparent diffusion coefficient (ADC) histograms retrospectively.

Authors: Tomohisa Moriya, Kazuhiro Saito, Yu Tajima, Taiyo L. Harada, Yoichi Araki, Katsutoshi Sugimoto and Koichi Tokuuye

Clinical and radiological features driving patient selection for antiangiogenic therapy in non-small cell lung cancer (NSCLC)

The use of antiangiogenic therapy in non-small cell lung cancer (NSCLC) requires thorough evaluation of patient characteristics in order to avoid potential safety issues, particularly pulmonary haemorrhage (PH...

Authors: Cesare Gridelli, Andrea Camerini, Giovanni Pappagallo, Angelo Pennella, Michele Anzidei, Massimo Bellomi, Roberta Buosi and Rosario Francesco Grasso

CT-perfusion measurements in pancreatic carcinoma with different kinetic models: Is there a chance for tumour grading based on functional parameters?

To evaluate the interchangeability of perfusion parameters obtained with help of models used for post-processing of perfusion-CT images in pancreatic adenocarcinoma and to determine the mean values and ranges ...

Authors: Sven Schneeweiß, Marius Horger, Anja Grözinger, Konstantin Nikolaou, Dominik Ketelsen, Roland Syha and Gerd Grözinger

Evaluation of tumor recurrences after radical prostatectomy using 18F-Choline PET/CT and 3T multiparametric MRI without endorectal coil: a single center experience

To evaluate and compare the utility of 18F-fluorocholine (18F-CH) PET/CT versus 3-Tesla multiparametric MRI (mpMRI) without endorectal coil to detect tumor recurrences in patients with biochemical relapse foll...

Authors: Felipe Couñago, Manuel Recio, Antonio Maldonado, Elia del Cerro, Ana Aurora Díaz-Gavela, Israel J. Thuissard, David Sanz-Rosa, Francisco José Marcos, Karmele Olaciregui, María Mateo and Laura Cerezo

How we read FCH-PET/CT for prostate cancer

Over the last decade, ¹⁸F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT) has gained in popularity for the staging and restaging of patients with prostate cancer (PCa). However, despit...

Authors: Jean-Mathieu Beauregard and Alexis Beaulieu

Can morphological MRI differentiate between primary central nervous system lymphoma and glioblastoma?

Primary central nervous system lymphoma (PCNSL) is a rare, aggressive brain neoplasm that accounts for roughly 2-6% of primary brain tumors. In contrast, glioblastoma (GBM) is the most frequent and severe glio...

Authors: H. Malikova, E. Koubska, J. Weichet, J. Klener, A. Rulseh, R. Liscak and Z. Vojtech

Utility of SUV_max on ¹⁸ F-FDG PET in detecting cervical nodal metastases

The presence of cervical lymph node metastasis is an important prognostic factor for patients with head and neck squamous cell carcinomas (HNSCC). Accurate assessment of lymph node metastasis in these patients...

Authors: Rebecca S. M. Lim, Shakher Ramdave, Paul Beech, Baki Billah, Md Nazmul Karim, Julian A. Smith, Adnan Safdar and Elizabeth Sigston

Impact of 3T multiparametric MRI and FDG-PET-CT in the evaluation of occult primary cancer with cervical node metastasis

This study aimed to determine the ability of multimodal evaluation with multiparametric 3T-MRI (MPMRI) and positron emission tomography - computed tomography (PET/CT) to detect cancer of unknown primary origin...

Authors: Mária Gődény, Zsolt Lengyel, Gábor Polony, Zoltán Takácsi Nagy, Gergely Léránt, Orsolya Zámbó, Éva Remenár, László Tamás and Miklós Kásler

Impact of combined FDG-PET/CT and MRI on the detection of local recurrence and nodal metastases in thyroid cancer

Suspected recurrence of thyroid carcinoma is a diagnostic challenge when findings of both a radio iodine whole body scan and ultrasound are negative. PET/CT and MRI have shown to be feasible for detection of r...

Authors: Johann-Martin Hempel, Roman Kloeckner, Sandra Krick, Daniel Pinto dos Santos, Simin Schadmand-Fischer, Patrick Boeßert, Sotirios Bisdas, Matthias M. Weber, Christian Fottner, Thomas J. Musholt, Mathias Schreckenberger and Matthias Miederer

Erratum to: A method to assess image quality for Low-dose PET: analysis of SNR, CNR, bias and image noise

Authors: Jianhua Yan, Josh Schaefferkoetter, Maurizio Conti and David Townsend

How We Read Oncologic FDG PET/CT

¹⁸F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy...

Authors: Michael S. Hofman and Rodney J. Hicks