Figure 4

Patient 4, 48 year-old male. Radiograph of resected vertebra demonstrates a radiodense lesion (a). On CT, areas of lysis are seen, portions of which compromise the posterior cortex (b and c). This area corresponds to high signal on T2-weighted MRI (d). e: Microscopically, atypical tissue transitions between chordoma (left) and BNCT (right) (H&E, obj 4). f: The chordomatous component is composed of cords of eosinophilic and vacuolated cells in a myxoid background (H&E, obj 10). g: The BNCT component consists of permeative sheets of adipocyte-like cells associated with bone sclerosis (H&E, obj 10).