Table 3 Univariate and multivariate survival analysis for recurrence-free survival
Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | ||
Age | (1-year increase) | 0.756 | 1.005 (0.973–1.038) |  |  |
Sex | Woman | Reference | 1.000 | Â | Â |
|  | Man | 0.544 | 0.801 (0.391–1.640) |  |  |
Tumor location | Left colon | Reference | 1.000 | Â | Â |
|  | Right colon | 0.480 | 1.320 (0.611–2.855) |  |  |
|  | Rectum | 0.578 | 1.371 (0.451–4.167) |  |  |
Serum CEA level | < 5 ng/ml | Reference | 1.000 |  |  |
|  | ≥ 5 ng/ml | 0.088 | 1.869 (0.912–3.828) |  |  |
Tumor size | (1 cm increase) | 0.102 | 1.077 (0.880–1.354) |  |  |
Tumor grade | Low-grade | Reference | 1.000 | Â | Â |
|  | High-grade | 0.777 | 1.149 (0.439–3.005) |  |  |
Lymphovascular invasion | Absent | Reference | 1.000 | Â | Â |
|  | Present | 0.080 | 1.388 (0.938–2.338) |  |  |
TNM stage | Stage I-II | Reference | 1.000 | Reference | 1.000 |
|  | Stage III-IV | 0.015 | 2.554 (1.195–5.460) | 0.031 | 2.341 (1.079–5.078) |
Adjuvant therapy | No | Reference | 1.000 | Â | Â |
|  | Yes | 0.201 | 0.556 (0.226–1.367) |  |  |
Maximum SUV | (1.0 increase) | 0.075 | 1.041 (0.980–1.102) |  |  |
MTV | (10.0 cm3 increase) | 0.425 | 1.054 (0.926–1.200) |  |  |
TLG | (10.0 g increase) | 0.617 | 0.999 (0.986–1.013) |  |  |
Mean SUV | (1.0 increase) | 0.185 | 0.884 (0.767–1.017) |  |  |
Median SUV | (1.0 increase) | 0.089 | 1.009 (0.974–1.045) |  |  |
CoV SUV | (0.10 increase) | 0.031 | 0.503 (0.269–0.942) | 0.019 | 0.484 (0.263–0.889) |
Kurtosis | (1.0 increase) | 0.930 | 1.018 (0.682–1.521) |  |  |
Skewness | (1.0 increase) | 0.811 | 1.151 (0.365–3.624) |  |  |
Entropy | (1.0 increase) | 0.433 | 1.277 (0.693–2.530) |  |  |
Uniformity | (0.10 increase) | 0.050 | 0.416 (0.173–1.000) | 0.664 | 0.984 (0.290–3.653) |
BM SUV | (1.0 increase) | 0.221 | 1.646 (0.742–3.652) |  |  |
BLR | (1.0 increase) | 0.044 | 5.128 (1.030–23.282) | 0.261 | 2.870 (0.456–18.049) |
Spleen SUV | (1.0 increase) | 0.293 | 1.766 (0.612–5.098) |  |  |
SLR | (1.0 increase) | 0.005 | 45.21 (3.212–636.387) | 0.020 | 24.901 (1.660–373.709) |