Skip to main content

Table 1 Characteristics of development and test cohorts

From: Preoperative prediction of early recurrence in resectable pancreatic cancer integrating clinical, radiologic, and CT radiomics features

 

Development cohort (n = 150)

Test cohort (n = 40)

P-value

Outcome

Recurrence within 1 year

55 (36.7)

17 (42.5)

0.62

Pre-operative clinical features

Age, years (mean ± SD)

66.3 ± 9.3

69.3 ± 8.9

0.06

Sex

  

0.68

 Male

69 (46.0)

18 (45.0)

 

 Female

81 (54.0)

22 (55.0)

 

CA19-9 (mean ± SD)

551.0 ± 1,291.6

176.6 ± 320.4

0.07

CT radiologic features

Tumor location

  

< 0.01

 Head/neck

52 (34.7)

24 (60.0)

 

 Body/tail

98 (65.3)

16 (40.0)

 

Abutment to the PV and/or SMV

27 (18.0)

6 (15.0)

0.83

Peripancreatic infiltration

72 (48.0)

19 (47.5)

> 0.99

Adjacent organ invasion

27 (18.0)

5 (12.5)

0.56

Enlarged lymph node

18 (12.0)

6 (15.0)

0.81

Obstructive pancreatitis

48 (32.0)

10 (25.0)

0.51

Upstream parenchymal atrophy

42 (28.0)

11 (27.5)

> 0.99

Main pancreatic duct dilatation

104 (69.3)

26 (65.0)

0.74

Post-operative features

Tumor size, cm

2.6 ± 0.8

2.8 ± 0.7

0.048

Tumor differentiation

  

0.76

 G1

7 (4.7)

2 (5.0)

 

 G2

117 (78.0)

33 (82.5)

 

 G3

26 (17.3)

5 (12.5)

 

T stage

  

0.86

 Tis

1 (0.7)

0 (0.0)

 

 T1

31 (20.7)

7 (17.5)

 

 T2

118 (78.7)

33 (82.5)

 

N stage

  

0.93

 N0

73 (48.7)

21 (52.5)

 

 N1

65 (43.3)

16 (40.0)

 

 N2

12 (8.0)

3 (7.5)

 

Resection margin

  

0.39

 R0

120 (80.0)

35 (87.5)

 

 R1

30 (20.0)

5 (12.5)

 

Adjuvant chemotherapy/CCRT

106 (70.7)

35 (87.5)

0.050

  1. Note: Unless otherwise indicated, data represent the number of patients, and numbers in parentheses indicate percentages
  2. CA 19-9, carbohydrate antigen 19-9; CCRT, concurrent chemoradiotherapy; PV, portal vein; SD, standard deviation; SMV, superior mesenteric vein