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Fig. 2 | Cancer Imaging

Fig. 2

From: Multiparametric bone MRI targeting aides lesion selection for CT-guided sclerotic bone biopsies in metastatic castrate resistant prostate cancer

Fig. 2

CT-guided bone biopsy target lesion selection process based on multiparametric bone MRI, considering high b-value DWI (b900) signal intensity (SI) ADC and rFF in a metastatic castrate resistant 74-year-old prostate cancer patient with multifocal sclerotic bone metastases, CT images for comparison. The anterior metastasis in the first row (arrow) shows low DWI SI, the posterior lesion (arrowhead) displays high ADC (> 1100 µm2/s) and high rFF (> 20%) and was thus not fit for biopsy. The pubic bone metastasis in the second row shows high DWI SI, ADC < 1100 µm2/s and rFF < 20% and was biopsied, biopsy provided sufficient malignant tumor cells for next-generation genomic sequencing. The ischial metastases in the third row displays high DWI signal, an ADC < 1100 µm2/s, but an rFF of 31% and was thus not considered for biopsy

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Cancer Imaging

ISSN: 1470-7330

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