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Table 5 VASARI features predicting MGMT unmethylated status resulted in 5 significant features with non-zero coefficients

From: Beyond invasive biopsies: using VASARI MRI features to predict grade and molecular parameters in gliomas

Selected VASARI features

Logistic LASSO coefficients

Category

OR (95% CI)

p-value

f6–proportion of non-enhancing

-0.176

(68–100%)

0.215 (0.067—0.687)

0.009

f13–definition of the non-enhancing margin

-0.019

   

f15–edema crosses midline

-0.351

(yes)

0.305 (0.125—0.742)

0.009

f25–calvarial modeling

-0.399

   

f29–longest diameter

-0.084

 

0.746 (0.599—0.929)

0.009

  1. Categories (within parentheses) have significant odds ratios compared to their base categories for predicting MGMT unmethylated status
  2. VASARI Visually AcceSAble Rembrandt Images, OR odds ratio, LASSO (Least Absolute Shrinkage and Selection Operator), MGMT Methylguanine-DNA-methyltransferase
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Cancer Imaging

ISSN: 1470-7330

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