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Table 4 VASARI features predicting IDH wildtype status resulted in 12 significant features with non-zero coefficients

From: Beyond invasive biopsies: using VASARI MRI features to predict grade and molecular parameters in gliomas

Selected VASARI features

Logistic LASSO coefficient

Category

OR (95% CI)

p-value

f1–tumor location

0.199

   

f3–eloquent brain

0.106

   

f5–proportion enhancing

0.240

(34–67%)

6.333 (1.854—21.638)

0.003

f6–proportion of non-enhancing

-0.214

   

f10–T1/FLAIR ratio

0.276

(infiltrative)

4.727 (1.587—14.074)

0.005

f11–thickness of enhancing margin

0.377

(thick/nodular)

6.328 (1.880—21.295)

0.003

f13–definition of the non-enhancing margin

-0.224

   

f22–non-contrast enhancing crosses midline

-0.191

   

f23–contrast-enhancing crosses midline

-1.077

   

f24–satellites

0.037

   

f29–longest diameter

-0.142

   

f30–perpendicular to longest diameter

-0.143

   
  1. Categories (within parentheses) have significant odds ratios compared to their base categories for predicting IDH wildtype status
  2. VASARI Visually AcceSAble Rembrandt Images, OR odds ratio, FLAIR fluid-attenuated inversion recovery, LASSO (Least Absolute Shrinkage and Selection Operator), IDH Isocitrate dehydrogenase