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Table 1 Clinical and pathological characteristics

From: Evaluating residual tumor after neoadjuvant chemotherapy for muscle-invasive urothelial bladder cancer: diagnostic performance and outcomes using biparametric vs. multiparametric MRI

Clinicopathological variable

Number (%) *

Age (years)

65 (59–72)

Gender

Male

36 (59.0%)

Female

25 (41.0%)

Clinical T stage

cT2

27 (44.3%)

cT3

20 (32.8%)

cT4

14 (23.0%)

Histological subtype

NOS

34 (55.7%)

NOS with glandular

2 (3.3%)

NOS with lymphoepithelioma-like

1 (1.6%)

NOS with microcystic

1 (1.6%)

NOS with micropapillary

2 (3.3%)

NOS with nested

1 (1.6%)

NOS with plasmacytoid

3 (4.9%)

NOS with sarcomatoid

3 (4.9%)

NOS with small cell

6 (9.8%)

NOS with squamous

8 (13.1%)

Type of neoadjuvant chemotherapy

Gemcitabine + cisplatin

40 (65.6%)

Gemcitabine + cisplatin + paclitaxel

6 (9.8%)

Gemcitabine + carboplatin

3 (4.9%)

Gemcitabine + carboplatin + paclitaxel

2 (3.3%)

Methotrexate + vinblastine + doxorubicin + cisplatin †

4 (6.6%)

Etoposide + Cisplatin ‡

4 (6.6%)

Etoposide + Carboplatin

2 (3.3%)

Type of surgery

Partial cystectomy

4 (6.6%)

Radical cystectomy

57 (93.4%)

Pathological staging on cystectomy

ypT0

19 (31.1%)

ypTa

2 (3.3%)

ypTis

6 (9.8%)

ypT1

7 (11.5%)

ypT2

7 (11.5%)

ypT3

15 (24.6%)

ypT4

5 (8.2%)

Time interval (days)

Neoadjuvant chemotherapy to MRI

14 (7–23)

MRI to cystectomy

33 (24–42)

Cystectomy to follow-up

461 (162–1048)

  1. MRI = magnetic resonance imaging; NOS = not otherwise specified
  2. * Number of patients with percentages in parentheses for categorical variables and medians with interquartile ranges (IQR) in parentheses for continuous variables
  3. † 3 of 4 with dose-dense regimen
  4. ‡ 1of 4 with Durvalumab