Table 3 Univariate analysis for metastasis
Variable | N0 (n = 117) | N1/N2 (n = 27) | P-value |
|---|---|---|---|
Gender | Â | Â | 0.040 |
Female | 73(62.4) | 11(40.7) | Â |
Male | 44(37.6) | 16(59.3) | Â |
Age (years) | Â | Â | 0.261 |
< 60 | 66(56.4) | 12(44.4) |  |
≥ 60 | 51(43.6) | 15(55.6) |  |
Family history of Lung Cancer | Â | Â | 0.675 |
No | 107(91.5) | 24(88.9) | Â |
Yes | 10(8.5) | 3(11.1) | Â |
History of malignancy | Â | Â | 0.497 |
No | 105(89.7) | 23(85.2) | Â |
Yes | 12(10.3) | 4(14.8) | Â |
Smoking index | Â | Â | 0.037 |
Nonsmoker | 80(68.4) | 12(44.4) | Â |
< 400 | 20(17.1) | 6(22.2) |  |
≥ 400 | 17(14.5) | 9(33.3) |  |
Surgery | Â | Â | 0.151 |
Lobectomy | 74(63.2) | 21(77.8) | Â |
Segmentectomy | 43(36.8) | 6(22.2) | Â |
Location | Â | Â | 0.998 |
Right upper lobe | 29(24.8) | 7(25.9) | Â |
Right middle lobe | 9(7.7) | 2(7.4) | Â |
Right lower lobe | 23(19.7) | 5(18.5) | Â |
Left upper lobe | 32(27.4) | 8(29.6) | Â |
Left lower lobe | 24(20.5) | 5(18.5) | Â |
Nodule type | Â | Â | 0.008 |
pSN | 25(21.4) | 0(0) | Â |
SN | 92(78.6) | 27(100) | Â |
Pathological type | Â | Â | 0.039 |
AIS | 3(2.6) | 0(0) | Â |
MIA | 19(16.2) | 0(0) | Â |
IA | 95(81.2) | 27(100) | Â |
Follow-up (days) | 176.4 ± 88.3 | 195.6 ± 107.3 | 0.395 |
Initial diameter (mm) | 11.25 ± 5.21 | 14.95 ± 5.59 | 0.010 |
Solid component (mm) | Â | Â | 0.047 |
< 5 | 14(12) | 0(0) |  |
≥ 5 | 103(88) | 27(100) |  |
C/T ratio | 0.92 ± 0.19 | 1.0 ± 0.0 | 0.000 |
Initial volume (mm3) | 1356.95 ± 1835.41 | 2896.88 ± 2785.87 | 0.010 |
Initial mass (g) | 1.23 ± 1.69 | 2.87 ± 2.82 | 0.007 |
Diameter increase (mm) | 1.43 ± 0.91 | 4.16 ± 2.18 | 0.000 |
Solid component increase (mm) | 1.48 ± 1.10 | 4.10 ± 2.27 | 0.000 |
Volume increase (mm3) | 302.96 ± 336.11 | 1936.66 ± 1415.01 | 0.000 |
Mass increase (g) | 0.33 ± 0.37 | 2.09 ± 1.56 | 0.000 |
Relative diameter change (%) | 14.63 ± 10.82 | 30.95 ± 19.32 | 0.000 |
Relative volume change (%) | 29.85 ± 18.51 | 87.51 ± 51.36 | 0.000 |
Relative mass change (%) | 34.76 ± 19.62 | 97.36 ± 54.70 | 0.000 |
VDTt (days) | 424 ± 217 | 248 ± 167 | 0.001 |
MDTt (days) | 378 ± 185 | 228 ± 158 | 0.001 |