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Table 2 Baseline characteristics of patients with and without disease recurrence

From: Analysis of preoperative computed tomography radiomics and clinical factors for predicting postsurgical recurrence of papillary thyroid carcinoma

Characteristic

All patients

(n = 280)

No recurrence

(n = 191)

Recurrence

(n = 89)

P-value

Clinicopathologic features

    

Age (years)a

40.74 ± 13.61

39.07 ± 11.91

44.31 ± 16.19

0.003*

Sex

   

0.019*

Male

94 (33.6)

55 (28.8)

39 (43.8)

 

female

186 (66.4)

136 (71.2)

50 (56.2)

 

Tumor size (mm)a

24.58 ± 14.61

22.74 ± 11.76

28.52 ± 18.84

0.002*

Bilaterality

   

0.005*

Absence

137 (48.9)

105 (55.0)

32 (36.0)

 

Presence

143 (51.1)

86 (45.0)

57 (64.0)

 

Multifocality

   

0.114

Absence

102 (36.4)

76 (39.8)

26 (29.2)

 

Presence

178 (63.6)

115 (60.2)

63 (70.8)

 

Extrathyroidal extension

   

0.119

Absence

17 (6.1)

15 (7.9)

2 (2.2)

 

Presence

263 (93.9)

176 (92.1)

87 (97.8)

 

Number of metastatic LNb

11 (4–19)

10 (3–17)

15 (8–24)

< 0.001*

Concomitant thyroid disease

   

0.067

Neither

73 (26.1)

44 (23.0)

29 (32.6)

 

Nodular goiter

142 (50.7)

96 (50.3)

46 (51.7)

 

Hashimoto’s thyroiditis

55 (19.6)

45 (23.6)

10 (11.2)

 

Both

10 (3.6)

6 (3.1)

4 (4.5)

 

Surgical option

   

0.678

Total thyroidectomy

237 (84.6)

160 (83.8)

77 (86.5)

 

Subtotal or semi-total thyroidectomy

43 (15.4)

31 (16.2)

12 (13.5)

 

T stage

   

0.001*

T1a

3 (1.1)

3 (1.6)

0 (0.0)

 

T1b

9 (3.2)

7 (3.7)

2 (2.2)

 

T2

3 (1.1)

3 (1.6)

0 (0.0)

 

T3

233 (83.2)

166 (86.9)

67 (75.3)

 

T4a

32 (11.4)

12 (6.3)

20 (22.5)

 

N stage

   

0.044*

N0

27 (9.6)

24 (12.6)

3 (3.4)

 

N1a

40 (14.3)

28 (14.7)

12 (13.5)

 

N1b

213 (76.1)

139 (72.8)

74 (83.1)

 

131I radiotherapy

   

0.044*

Not received

152 (54.3)

112 (58.6)

40 (44.9)

 

Received

128 (45.7)

79 (41.4)

49 (55.1)

 

Family history

   

0.576

Absence

266 (95.0)

180 (94.2)

86 (96.6)

 

Presence

14 (5.0)

11 (5.8)

3 (3.4)

 

CT features

    

Shape

   

0.842

Regular

12 (4.3)

9 (4.7)

3 (3.4)

 

Irregular

268 (95.7)

182 (95.3)

86 (96.6)

 

Margin

   

0.510

Well-defined

11 (3.9)

9 (4.7)

2 (2.2)

 

Ill-defined

269 (96.1)

182 (95.3)

87 (97.8)

 

Calcification

   

0.275

Absence

125 (44.6)

90 (47.1)

35 (39.3)

 

Presence

155 (55.4)

101 (52.9)

54 (60.7)

 

CT-reported LN status

   

0.009*

Negative

31 (11.1)

28 (14.7)

3 (3.4)

 

Positive

249 (88.9)

163 (85.3)

86 (96.6)

 
  1. Unless otherwise indicated, data are the number of patients and data in parentheses are percentages
  2. a Data are means ± standard deviation
  3. b Data are medians, with interquartile range in parentheses
  4. *Statistically significant difference
  5. CT: computed tomography; LN: lymph nodes