Prognostic value of MRI volumetric parameters in non-small cell lung cancer patients after immune checkpoint inhibitor therapy: comparison with response assessment criteria

Table 4 Prediction of Overall Survival According to the Difference in Quantitative Measurements between Best Overall Response (BOR) and Baseline MRI

Quantitative Assessment	Overall Survival
Changes in sum of the longest diameters (SLD) (mm)	Hazard Ratio	95% CI	P-value
mRECIST	1.07	1.005–1.14	0.035
RANO-BM	1.07	0.99–1.16	0.077
iRANO-BM	1.03	0.99–1.07	0.172
Change in volumetry (mm³)
Total volume of BM	5.87	1.46–23.64	0.013

Note: Changes in sum of the longest diameters (SLDs) indicates the value of the baseline sum of the longest diameters (SLD) minus the SLD at the date of the BOR, and change in volumetry indicates the total volume at baseline minus the total volume at BOR date
Hazard ratios reported here indicate the relative change in hazard that a 1 unit (10 000 voxels) increase in each imaging parameter incurs. BM, brain metastases

ISSN: 1470-7330