Table 2 Results of multiple cox regression

TNM stage

 II

65

Reference

Reference

 III

42

1.48 (1.04–2.47)

0.13

1.42 (1.06–2.34)

0.17

 IV

19

2.10 (1.09–4.04)

< 0.05

1.98 (1.02–3.84)

< 0.05

S2

< 0.001

< 0.05

 Over-expression

79

Reference

Reference

 Under-expression

47

2.26 (1.40–3.67)

2.23 (1.36–3.65)

S3

< 0.05

< 0.05

 Over-expression

92

Reference

Reference

 Under-expression

34

0.48 (0.29–0.79)

0.55 (0.33–0.90)