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Table 3 Comparison of lesion conspicuity between the standard and RPP groups

From: Renal protection CT protocol using low-dose and low-concentration iodine contrast medium in at-risk patients of HCC and with chronic kidney disease: a randomized controlled non-inferiority trial

 

Estimate (95% CI)

Difference (95% CI)

P-value

Standard group iDose (A)

RPP group

50 keV (B)

RPP group DL-iodine boosting (C)

(A) vs. (B)

(A) vs. (C)

(A) vs.

(B)

(C)

Arterial phase

All FLLs (n = 62)

2.21 (1.24, 3.18)

2.49 (2.14, 2.84)

2.05 (1.80, 2.31)

0.28 (− 0.75, 1.31)

−0.16 (− 1.16, 0.84)

0.596

0.757

< 20 mm (n = 50)

2.13 (1.15, 3.10)

2.15 (2.02, 2.28)

1.85 (1.66, 2.04)

0.02 (− 0.97, 1.00)

−0.28 (− 1.27, 0.72)

0.971

0.586

≥ 20 mm (n = 12)

2.75 (1.88, 3.62)

3.32 (2.79, 3.85)

2.54 (1.97, 3.10)

0.57 (− 0.44, 1.59)

−0.21 (− 1.25, 0.82)

0.269

0.685

Portal venous phase

All FLLs (n = 62)

2.19 (1.34, 3.04)

2.56 (2.04, 3.08)

2.32 (1.87, 2.77)

0.37 (− 0.62, 1.37)

0.13 (− 0.83, 1.09)

0.464

0.787

< 20 mm (n = 50)

2.13 (1.29, 2.96)

2.19 (2.09, 2.29)

1.91 (1.71, 2.12)

0.06 (− 0.78, 0.90)

−0.22 (− 1.08, 0.64)

0.884

0.621

≥ 20 mm (n = 12)

2.60 (1.68, 3.52)

3.46 (2.12, 4.81)

3.32 (2.35, 4.29)

0.86 (− 0.76, 2.49)

0.72 (− 0.61, 2.06)

0.298

0.290

  1. Note: CI = confidence interval, DL = deep learning, FLLs = focal liver lesions, RPP = renal protection protocol. P-value < 0.017 indicated a significant difference