|  | Validation set | Independent test set | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Data | Model | DSC | ACC | SEN | SPE | IOU | ASSD | HD95 | DSC | ACC | SEN | SPE | IOU | ASSD | HD95 |
 | U-Net | 86.15 | 99.41 | 88.86 | 99.66 | 78.15 | 1.74 | 6.89 | 87.49 | 99.40 | 89.19 | 99.68 | 78.36 | 1.08 | 3.66 |
 | nnUNet | 86.49 | 99.42 | 86.95 | 99.73 | 78.63 | 1.15 | 4.81 | 87.58 | 99.40 | 87.10 | 99.77 | 78.37 | 0.59 | 2.95 |
 | COM-Net | 83.78 | 99.35 | 86.61 | 99.66 | 78.27 | 1.85 | 6.80 | 86.69 | 99.39 | 89.79 | 99.67 | 77.27 | 1.59 | 5.05 |
All | MTTU-Net | 85.91 | 99.41 | 87.69 | 99.68 | 78.02 | 1.21 | 4.85 | 86.88 | 99.40 | 89.27 | 99.69 | 77.64 | 1.40 | 4.20 |
 | Ours | 86.22 | 99.41 | 87.93 | 99.69 | 78.86 | 0.65 | 2.55 | 87.60 | 99.40 | 89.10 | 99.71 | 78.40 | 0.70 | 2.63 |
 |  + clinical characteristics | 85.22 | 99.4 | 86.59 | 99.71 | 74.91 | 0.91 | 3.59 | 86.62 | 99.36 | 86.54 | 99.72 | 76.92 | 0.60 | 2.82 |
 | U-Net | 86.03 | 99.57 | 88.57 | 99.75 | 79.49 | 1.49 | 6.13 | 88.09 | 99.50 | 89.75 | 99.71 | 79.10 | 1.49 | 4.58 |
 | nnUNet | 87.48 | 99.63 | 87.79 | 99.83 | 80.54 | 0.49 | 2.19 | 88.43 | 99.54 | 87.55 | 99.80 | 79.53 | 0.58 | 2.29 |
 | COM-Net | 82.40 | 99.48 | 85.69 | 99.74 | 80.29 | 2.20 | 8.58 | 86.01 | 99.48 | 90.19 | 99.68 | 76.52 | 2.66 | 7.87 |
Grade | MTTU-Net | 85.54 | 99.55 | 86.97 | 99.74 | 80.22 | 0.86 | 3.05 | 85.84 | 99.49 | 89.21 | 99.72 | 76.60 | 2.47 | 6.70 |
II | Ours | 86.58 | 99.59 | 88.32 | 99.77 | 80.91 | 0.62 | 2.21 | 88.50 | 99.53 | 89.16 | 99.75 | 79.68 | 0.67 | 2.52 |
 |  + clinical characteristics | 85.12 | 99.57 | 87.2 | 99.78 | 74.88 | 1.06 | 4.12 | 87.70 | 99.51 | 87.52 | 99.74 | 78.52 | 0.62 | 3.01 |
 | U-Net | 85.99 | 99.22 | 87.94 | 99.60 | 78.35 | 1.36 | 3.15 | 85.09 | 99.42 | 87.82 | 99.68 | 75.26 | 1.01 | 4.23 |
 | nnUNet | 85.18 | 99.17 | 84.06 | 99.65 | 78.57 | 0.66 | 2.69 | 85.87 | 99.41 | 87.87 | 99.77 | 76.09 | 0.72 | 3.28 |
 | COM-Net | 84.09 | 99.12 | 86.08 | 99.55 | 78.63 | 1.62 | 5.66 | 85.38 | 99.38 | 90.84 | 99.64 | 75.42 | 1.30 | 4.84 |
Grade | MTTU-Net | 86.02 | 99.20 | 87.62 | 99.64 | 78.73 | 0.70 | 3.00 | 86.16 | 99.41 | 89.32 | 99.69 | 76.36 | 0.88 | 3.12 |
III | Ours | 86.64 | 99.25 | 88.65 | 99.60 | 78.89 | 0.69 | 2.61 | 85.44 | 99.37 | 90.19 | 99.66 | 75.4 | 0.90 | 3.45 |
 |  + clinical characteristics | 85.25 | 99.14 | 85.07 | 99.63 | 74.89 | 0.65 | 2.74 | 85.11 | 99.34 | 86.7 | 99.68 | 74.73 | 0.60 | 2.55 |
 | U-Net | 86.57 | 99.17 | 90.22 | 99.51 | 76.81 | 2.62 | 11.42 | 88.59 | 99.28 | 89.58 | 99.65 | 79.82 | 0.67 | 2.23 |
 | nnUNet | 85.04 | 99.09 | 86.99 | 99.55 | 76.94 | 3.09 | 12.68 | 87.90 | 99.24 | 86.04 | 99.75 | 78.75 | 0.51 | 3.43 |
 | COM-Net | 86.90 | 99.19 | 89.23 | 99.56 | 76.24 | 1.15 | 3.29 | 88.41 | 99.29 | 88.57 | 99.69 | 79.46 | 0.61 | 2.07 |
Grade | MTTU-Net | 86.72 | 99.21 | 89.47 | 99.55 | 75.62 | 2.41 | 10.54 | 88.55 | 99.29 | 89.31 | 99.66 | 79.73 | 0.59 | 2.24 |
IV | Ours | 85.02 | 99.10 | 86.47 | 99.58 | 76.98 | 0.71 | 3.36 | 88.20 | 99.28 | 88.22 | 99.70 | 79.20 | 0.59 | 2.15 |
 |  + clinical characteristics | 85.43 | 99.15 | 86.21 | 99.59 | 74.99 | 0.74 | 2.91 | 86.55 | 99.20 | 85.34 | 99.72 | 76.77 | 0.57 | 2.81 |