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Table 4 PPV, NPV, sensitivity, specificity and diagnostic accuracy for SSR-PET/CT. PPV, positive predictive value; NPV, negative predictive value.

From: Diagnostic accuracy of SSR-PET/CT compared to histopathology in the identification of liver metastases from well-differentiated neuroendocrine tumors

 

Biopsy

Re-biopsy (reference standard)

PPV

91.0% (95%CI: 84.8%, 95.3%)

95.5% (95%CI: 90.4%, 98.3%)

NPV

0% (95%CI: 0%, 45.9%)

0% (95%CI: 0%, 45.9%)

Sensitivity

95.2% (95%CI: 90.0%, 98.3%)

95.5% (95%CI: 90.4%, 98.3%)

Specificity

0% (95%CI: 0%, 26.5%)

0% (95%CI: 0%, 45.9%)

Accuracy

87.1% (95%CI: 80.0%, 92.1%)

91.4% (95%CI: 85.4%, 95.5%)

  1. PPV, positive predictive value; NPV, negative predictive value
  2. NPV and Specificity are both recorded as 0% due to the deliberate study design focusing on a patient cohort with a notably high prevalence of liver metastases.