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Table 1 The measurements of APTw-SI and MTR in six representative positions and intra- and inter-observer agreements

From: Amide proton transfer (APT) and magnetization transfer (MT) in predicting short-term therapeutic outcome in nasopharyngeal carcinoma after chemoradiotherapy: a feasibility study of three-dimensional chemical exchange saturation transfer (CEST) MRI

  

Reader 1

Reader 2

Agreement

First measurements

Second measurements

P Value

First measurements

P Value

Intra-observer

Inter-observer

APTw-SI:

MTRasym (%)

R1

3.369 ± 2.742 (1.786–4.952)

3.424 ± 2.335 (2.076–4.772)

0.908

3.180 ± 2.399 (1.795–4.565)

0.330

0.862

0.981

R2

3.309 ± 2.653 (1.778–4.841)

2.652 ± 1.901 (1.555–3.750)

0.123

3.383 ± 2.748 (1.796–4.970)

0.712

0.883

0.981

R3

2.881 ± 2.327 (1.537–4.224)

2.622 ± 1.821 (1.571–3.673)

0.435

3.199 ± 2.941 (1.501–4.898)

0.384

0.910

0.934

L1

3.442 ± 2.430 (2.039–4.845)

3.019 ± 1.912 (1.915–4.123)

0.356

3.197 ± 2.704 (1.636–4.759)

0.224

0.833

0.980

L2

3.345 ± 1.989 (2.196–4.494)

3.162 ± 2.053 (1.977–4.347)

0.598

3.302 ± 1.823 (2.250–4.355)

0.869

0.891

0.933

L3

2.624 ± 2.032 (1.451–3.798)

2.314 ± 1.334 (1.543–3.084)

0.401

2.591 ± 1.892 (1.499–3.684)

0.919

0.821

0.899

MTR (%)

R1

38.884 ± 3.354 (36.947–40.820)

38.660 ± 4.032 (36.332–40.988)

0.801

39.194 ± 2.272 (37.882–40.506)

0.393

0.763

0.929

R2

30.836 ± 3.300 (28.931–32.742)

30.189 ± 2.734 (28.611–31.768)

0.265

31.207 ± 2.650 (29.677–32.737)

0.400

0.867

0.924

R3

35.332 ± 2.489 (33.895–36.769)

35.140 ± 2.014 (33.978–36.303)

0.547

34.443 ± 1.946 (33.319–35.567)

0.128

0.736

0.930

L1

38.856 ± 2.913 (37.174–40.537)

38.999 ± 3.150 (37.180–40.818)

0.846

38.346 ± 3.049 (36.586–40.107)

0.319

0.753

0.895

L2

30.400 ± 2.432 (28.996–31.804)

30.530 ± 2.608 (29.024–32.036)

0.822

30.491 ± 2.272 (29.179–31.802)

0.809

0.786

0.965

L3

32.992 ± 1.684 (32.020–33.964)

32.944 ± 2.161 (31.697–34.192)

0.902

33.114 ± 1.997 (31.961–34.267)

0.612

0.842

0.940

  1. Note: All values were shown in arithmetic mean ± standard deviation, and the 95% confidence interval for the mean was included in parentheses. APTw-SI: amide proton transfer weighted signal intensity; MTR: magnetization transfer ratio; MTRasym: the asymmetric magnetization transfer ratio; R1: right longus capitis, R2: right tensor veli palatini, R3: right medial pterygoid, L1: left longus capitis, L2: left tensor veli palatini, L3: left medial pterygoid. P > 0.05 was considered not statistically significant.