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Fig. 8 | Cancer Imaging

Fig. 8

From: Amide proton transfer (APT) and magnetization transfer (MT) in predicting short-term therapeutic outcome in nasopharyngeal carcinoma after chemoradiotherapy: a feasibility study of three-dimensional chemical exchange saturation transfer (CEST) MRI

Fig. 8

 A 47-year-old male patient with nasopharyngeal carcinoma presented with residual lesions after chemoradiotherapy. T2WI sequence (A), T1WI contrast enhancement sequence (B), rFOV DWI sequence (C), and ADC map (D) showed the location of huge tumors in the right nasopharynx. MTR (7.0ppm) color maps (E) and APTw-SI:MTRasym (3.5ppm) color maps (F) showed that the tumor is of equal or high signal and of slightly low signal, respectively. Based on B0 map (G), tumor ROI showed homogenous and reasonable phase difference (< 60 Hz) compared to nasal cavity. MRI examination at the end of induction chemotherapy showed that the tumor had regression significantly (H, I). MRI examinations and electronic nasopharyngoscopy at the end of chemoradiotherapy showed that the tumor had small residual lesions (partial response, PR) (yellow arrow) and was classified into the residual group (J, K). MRI examinations at 6 months (L, M) after the last chemoradiotherapy treatment showed the tumor had completely disappeared and it verifies the previous judgment. Hematoxylin-eosin staining of pathological biopsy showed differentiated nonkeratinizing nasopharyngeal carcinoma (N)

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Cancer Imaging

ISSN: 1470-7330

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