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Table 3 The change of FDG uptake for reference sites after DEX suppression in the patients with CD

From: Dexamethasone suppression for 18F-FDG PET/CT to localize ACTH-secreting pituitary tumors

SUVmean

Baseline

18F-FDG PET/CT

DEX suppression 18F-FDG PET/CT

Wilcoxon Z

P value

Normal pituitary gland

3.50(2.40–5.30)

3.80(2.00–5.00)

-1.554

0.120

Cerebellum

7.65(4.50–10.80)

6.40(2.60–12.00)

-2.730

0.006*

Thalamus

8.70(4.40–22.70)

11.20(6.40–17.5)

-2.584

0.010*

White matter

2.60(2.00–5.70)

2.90(1.90–4.70)

-0.726

0.468

 Gy matter

6.25(2.50–15.00)

7.95(5.00–11.90)

-2.582

0.010*

  1. FDG, fluorodeoxyglucose; DEX, dexamethasone; CD, Cushing disease; SUVmean, mean standardized uptake value; 18F-FDG-PET/CT; 18 F-fluorodeoxyglucose positron emission tomography/computed tomography