Table 1 Patients’ imaging and clinical characteristics
From: Dexamethasone suppression for 18F-FDG PET/CT to localize ACTH-secreting pituitary tumors
Total (N = 22) | |
|---|---|
Age at diagnosis (years) | 37.50 (13.00–56.00) |
Sex | |
Male (%) | 2/22 (9.09%) |
Female (%) | 20/22 (90.91%) |
24 h UFC (µg/day) | 443.35 (93.20–4452.20) |
Preop ACTH level (pg/mL) | 36.16 (5.69–91.82) |
Preop cortisol level (µg/dL) | 18.55 (5.50–40.40) |
Nadir cortisol on the HD DST (µg/dL) | 2.40 (0.40–14.36) |
Suppression on the 1-mg ON DST | 0/22 (0.00%) |
Suppression on the HD DST | 21/22 (95.45%) |
Result of TSA surgery | |
Remission (%) | 18/22 (81.82%) |
Delayed remission (%) | 3/22 (13.64%) |
No remission (%) | 1/22 (4.56%) |
Size on MRI (mm) | 7.85 (2.00–28.00) |
Ki-67 | |
< 1 | 6/17(35.29%) |
1–2 | 8/17(47.06%) |
≥ 2 | 3/17(17.65%) |
Knosp classification (%) | |
0 | 15/20 (75.00%) |
1 | 1/20 (5.00%) |
2 | 0/20 (0.00%) |
3a/b | 1/20 (5.00%) |
4 | 3/20 (15.00%) |
Baseline18F-FDG PET/CT | |
Adenoma SUVmean | 4.60(2.80–8.30) |
Adenoma SUVmax | 5.05(3.20–8.60) |
18F-FDG PET/CT after DEX suppression | |
Adenoma SUVmean | 4.50(2.10–7.00) |
Adenoma SUVmax | 4.70(2.50–7.50) |