Fig. 4
Comparison of Al18F-NOTA-FAPI-04 Uptake in PDAC and Tumor-induced Pancreatitis. a. The mean level of Al18F-NOTA-FAPI-04 uptake values of the PDAC was higher than that of pancreatitis in both SUVmax-30min (10.4±2.0 vs. 7.3±2.0, P < 0.01) and SUVmax-1h (10.2±2.0 vs. 6.6±2.0, P < 0.01) subgroups. b. The mean level of Al18F-NOTA-FAPI-04 uptake values of the PDAC was higher than that of pancreatitis in both SUVmean-30min (4.7±1.0 vs. 3.5±1.0, P < 0.05) and SUVmean-1h (4.4±1.0 vs. 2.9±0.9, P < 0.01) subgroups. c. Female, 71 years old, Al18F-NOTA-FAPI-04 PET/CT at 15min, 30min, and 1h showed continued high uptake of PDAC (white and black arrows) located in the head of the pancreas (SUVmax-15min=10.5, SUVmax-30min=10.5, SUVmax-15min=7.7), while pancreatitis (red arrows) showed a decreasing uptake over time (SUVmax-15min=10.1, SUVmax-30min=7.4, SUVmax-15min=4.2). d. The violin plot showed that △SUVmax-1, △SUVmax-2, and △SUVmean-2 of PDAC and pancreatitis were statistically different