Fig. 4
From: Differentiating brain metastasis from glioblastoma by time-dependent diffusion MRI
A 69-year-old man with a brain metastasis from colon cancer. A contrast-enhanced T1-weighted image with a region of interest of the enhancing region (red line) (a), a FLAIR image with a region of interest of peritumoral region (orange line) (b), an apparent diffusion coefficient (ADC) map derived from pulsed gradient spin-echo (PGSE) DWI at an effective diffusion time (Δeff) of 44.5 ms (c), an ADC map derived from oscillating gradient spin-echo (OGSE) DWI at an Δeff of 7.1 ms (d), and maps of ADC change between PGSE DWI and OGSE DWI (cADC) (e) and relative ADC change between PGSE DWI and OGSE DWI (rcADC) (f). The ADC values in the tumor appear higher at short Δeff values than at long Δeff setting. Large changes in cADC and rcADC are noted between the OGSE and PGSE sequences in the tumor