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Table 3 Summary of prognostic factors for overall survival in liver transplantation recipients

From: Newly developed sarcopenia after liver transplantation, determined by a fully automated 3D muscle volume estimation on abdominal CT, can predict post-transplant diabetes mellitus and poor survival outcomes

 

Univariable analysis

Multivariable analysis

HR (95% CI)

P

HR (95% CI)

P

Sex (Male: Female)

0 (1.73E-55.4E)

0.962

  

Age (years)

0.98 (0.92-1.04)

0.556

  

BMI, before LT (kg/m2)

0.93 (0.79-1.09)

0.373

  

BMI, 1 year after LT (cm2/m2)

0.83 (0.71-0.98)

0.025

1.19 (0.61-2.33)

0.61

BMI, 2 years after LT (cm2/m2)

0.82 (0.69-0.97)

0.019

0.75 (0.39-1.43)

0.38

LDLT

0.86 (0.34-3.55)

0.862

  

Underlying malignancy

0.99 (0.31-3.19)

0.998

  

SMI, before LT (cm2/m2)

1.02 (0.97-1.09)

0.415

  

SMI, 1 year after LT (cm2/m2)

0.98 (0.93-1.05)

0.627

  

SMI, 2 years after LT (cm2/m2)

0.96 (0.91-1.03)

0.253

  

PTDM

0.89 (0.15-9.08)

0.885

  

HTN after LT

0 (1.21E-57.2E)

0.963

  

Renal failure

1.46 (0.19-11.2)

0.715

  

Chronic rejection

0 (3.25E-16.8E)

0.969

  

MELD

1.14 (1.02-1.28)

0.023

1.15 (1.01-1.31)

0.03

ND-sarcopenia

6.51 (2.12-19.9)

0.001

3.34 (1.05-10.7)

0.04

Post-LT sarcopenia

3.99 (1.04-15.4)

0.044

0 (1.04E-5.99E)

0.95

  1. HR Hazard ratio, BMI Bone mass index, SMI Skeletal muscle index, PTDM Post-transplant diabetes mellitus, HTN Hypertension, LT Liver transplantation, ND Newly developed, MELD Model for end-stage liver disease