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Table 3 Univariate and multivariate analysis of influencing factors (Logistic regression)

From: Preoperative contrast-enhanced CT imaging and clinicopathological characteristics analysis of mismatch repair-deficient colorectal cancer

Characteristic

Univariable

Multivariable

N

Event N

ORa

95% CIa

p-value

N

Event N

ORa

95% CIa

p-value

Tumour location

 Left-hemi colon

169

10

—

—

 

169

10

—

—

 

 Right-hemi colon

112

22

3.89

1.81, 8.92

 < 0.001

112

22

2.90

1.10, 8.19

0.036

Differentiation grade

 Moderate

213

13

—

—

      

 High

9

1

1.92

0.10, 11.7

0.55

     

 Low

34

7

3.99

1.40, 10.7

0.007

     

 Mucinous adenocarcinoma

25

11

12.1

4.58, 32.3

 < 0.001

     

Mucinous component

 No

232

16

—

—

      

 Yes

49

16

6.55

2.98, 14.5

 < 0.001

     

N stage

 N0

168

25

—

—

      

 N1 + N2

113

7

0.38

0.15, 0.86

0.029

     

CEA

281

32

0.98

0.94, 1.00

0.16

     

CEA status

 Negative

192

28

—

—

 

192

28

—

—

 

 Positive

89

4

0.28

0.08, 0.73

0.019

89

4

0.07

0.01, 0.31

0.002

No. of lymph node metastasis

281

32

0.57

0.31, 0.84

0.024

281

32

0.45

0.21, 0.70

0.008

LN positive ratio

281

32

0.00

0.00, 0.03

0.026

     

LN yield number

281

32

1.03

1.00, 1.06

0.073

     

Tumour long axes in the gross specimen

281

32

1.33

1.14, 1.56

 < 0.001

     

Tumour short axes in the gross specimen

281

32

1.44

1.19, 1.75

 < 0.001

     

Maximum tumour area

281

32

1.03

1.01, 1.04

 < 0.001

     

Enhancement degree

 Hyper-/isoenhancement

236

16

—

—

      

 Hypoenhancement

45

16

7.59

3.43, 16.9

 < 0.001

     

Enhancement pattern

 Homogenous

195

11

—

—

 

195

11

—

—

 

 Inhomogenous

86

21

5.40

2.52, 12.2

 < 0.001

86

21

2.55

0.84, 7.49

0.089

Hypoattenuation-within-tumour ratio

  < 1/3

245

16

—

—

 

245

16

—

—

 

 1/3–2/3

13

5

8.95

2.47, 30.2

 < 0.001

13

5

6.05

1.20, 33.0

0.031

  > 2/3

23

11

13.1

5.00, 34.9

 < 0.001

23

11

36.7

8.47, 220

 < 0.001

Largest LN short diameter

281

32

1.09

0.95, 1.25

0.19

     

CT LN greater or equal to 5 mm

281

32

1.02

0.95, 1.09

0.51

     

CT LN greater or equal to 8 mm

281

32

1.10

0.96, 1.25

0.15

281

32

1.32

1.06, 1.64

0.010

  1. LN Lymph node, CT LN greater or equal to 8 mm = Number of lymph nodes with long diameter ≥ 8 mm
  2. aOR Odds Ratio, CI Confidence Interval