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Table 3 Overview of thromboembolic (CTCAE grade 1-5) adverse events

From: Heparin reversal with protamine sulfate after Percutaneous Hepatic Perfusion (PHP): is less more?

Group

Adverse event

Area

Days after PHP

treatment

sequalae

n

groupPRO

Ischemic stroke

MCA

1st

none

none

1

groupPRO

Ischemic stroke

Bilateral PCA

4th

none

none

1

groupPRO

Ischemic stroke

PCA

6th

none

none

1

groupPRO

Ischemic stroke

PCA

5th

none

none

1

groupPRO

Ischemic stroke; PE; DVT

Basilar artery (stroke)

2nd

Thrombectomy,

anticoagulation

none

1

groupPRO

Ischemic stroke

MCA and ACA

1st

Thrombectomy,

anticoagulation

death

1

groupPRO

Ischemic stroke

MCA (and ACA)

1st

Thrombectomy,

anticoagulation

yes

1

groupPRO

NSTEMI

LAD

1st

PTCA

none

1

groupPRO

DVT

Femoral and popliteal vein

1st week

Anticoagulation

none

1

groupPRO

PE

Central pulmonary arteries

2nd

Anticoagulation

none

1

  1. Day of the PHP procedure = 1st day
  2. CTCAE Common Terminology Criteria for Adverse Events, PHP Percutaneous hepatic perfusion, MCA Middle cerebral artery, PCA Posterior cerebral artery, ACA Anterior cerebral artery, NSTEMI Non-ST-segment elevation myocardial infarction, LAD Left anterior descending artery, PTCA Percutaneous transluminal coronary angioplasty, DVT Deep vein thrombosis, PE Pulmonary embolism