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Table 4 Performance evaluation of ADC parameters for predicting PD-L1 expression status

From: Reproducibility and usefulness of quantitative apparent diffusion coefficient measurements for predicting program death-ligand 1 expression in nasopharyngeal carcinoma

ADC parameters

AUC(95% CI)

Cut off value

Sensitivity

Specificity

1.5-T MRI cohort

    

ADCmean (×10− 6 mm2/s)

0.756 (0.651, 0.861)

864.00

81.82% (36/44)

68.29% (28/41)

ADCmin (×10− 6 mm2/s)

0.689 (0.576, 0.802)

747.00

84.09% (37/44)

53.66% (22/41)

ADCmax (×10− 6 mm2/s)

0.733 (0.626, 0.839)

971.00

77.27% (34/44)

68.29% (28/41)

3.0-T MRI cohort

    

ADCmean (×10− 6 mm2/s)

0.820 (0.703, 0.937)

876.00

87.50% (21/24)

76.00% (17/25)

ADCmin (×10− 6 mm2/s)

0.755 (0.616, 0.894)

758.00

75.00% (18/24)

76.00% (19/25)

ADCmax (×10− 6 mm2/s)

0.760 (0.627, 0.893)

1027.00

87.50% (21/24)

60.00% (15/25)

  1. Abbreviations: ADC apparent diffusion coefficient, ADCmean Mean ADC, ADCmin Minimum ADC, ADCmax Maximal ADC, AUC area under the ROC curve