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Table 2 Sonographic characteristics of the l-MTC group compared with the benign group

From: Using preoperative ultrasound vascularity characteristics to estimate medullary thyroid cancer

Variable

l-MTC

Benign Group

P

Age, y (median)

48.00

54.61

0.08

Sex (female/male)

17/14

14/28

0.88

Tumour size (cm)

2.15

2.07

0.79

Echogenicity

  

0.30

Hyperechogenicity/Isoechogenicity

5 (16.1%)

16 (25.8%)

 

Hypoechogenicity

26 (83.9%)

46 (74.2%)

 

Cystic change (%)

20 (64.5%)

29 (46.8%)

0.10

ATA classification

  

0.06

Intermediate Suspicion

22 (71.0%)

31 (50.0%)

 

Low Suspicion

9 (29.0%)

21 (33.9%)

 

Very low Suspicion

0

10 (16.1%)

 

Vascularity

   

CHAMMAS pattern [15]

  

< 0.001

Pattern II

0

14 (22.6%)

 

Pattern III

4 (12.9%)

28 (45.2%)

 

Pattern IV

27 (87.1%)

20 (32.3%)

 

CHEN pattern [16]

  

< 0.001

Pattern I

0

14 (22.6%)

 

Pattern II b

0

19 (30.6%)

 

Pattern III c

0

13 (21.0%)

 

Pattern IV a

31 (100%)

16 (25.8%)

 

Penetrating branching vascularity

  

< 0.001

YES

23 (74.2%)

5 (4.8%)

 

NO

8 (25.8%)

59 (95.2%)

 
  1. Abbreviations: y, years old; l-MTC, ultrasound-low suspicious medullary thyroid carcinoma; ATA, American Thyroid Association