Skip to main content

Table 5 Univariate and multiple analysis of prognostic factor for OS

From: Safety, efficacy, and survival of drug-eluting beads-transarterial chemoembolization vs. conventional-transarterial chemoembolization in advanced HCC patients with main portal vein tumor thrombus

 

Univariate Analysis

Multivariate Analysis

Variable

No. of Patients (n = 83)

Median OS

P-Value

Hazard Ratio *

P-Value

Methods

  

 < 0.001

 

0.001

 DEB-TACE

42

12.0 (8.7–15.3)

 

1

 

 C-TACE

41

5.0 (3.8–6.2)

 

2.4 (1.4–4.1)

 

Child–Pugh

  

0.663

  

 A

66

7.0 (3.8–10.1)

   

 B

17

9.0 (1.7–16.3)

   

AFP value

  

0.297

  

 ≤ 400

37

9.0 (5.5–12.5)

   

 > 400

46

6.0 (4.2–7.8)

   

APS

  

 < 0.001

 

0.019

 Present

34

4.0 (2.7–5.3)

 

1.9 (1.1–3.2)

 

 Absent

49

12.0 (9.6–14.4)

 

1

 

HVI

  

0.133

  

 Present

55

5.0 (3.0–7.0)

   

 Absent

28

10.0 (5.8–14.2)

   

EHS

  

0.831

  

 Present

26

5.0 (0.3–9.7)

   

 Absent

57

8.0 (5.1–10.9)

   

Maximum Diameter

  

0.086

 

0.456

 ≤ 5 cm

18

12.0 (5.0–19.0)

   

 > 5 cm

65

6.0 (3.8–8.2)

   

Capsular Infiltration

  

0.001

 

0.015

 Non-infiltration

33

12.0 (9.1–14.9)

 

1

 

 Infiltration

50

5.0 (3.5–6.5)

 

1.9 (1.1–3.3)

 

Tumor Numbers

  

0.533

  

 Single

17

13.0 (0.0–28.2)

   

 Multiple

66

8.0 (5.6–10.4)

   

DCR

  

 < 0.001

 

 < 0.001

 CR + PR + SD

54

12.0 (9.3–14.7)

 

1

 

 PD

29

4.0 (3.4–4.6)

 

4.0 (2.2–7.3)

 

Follow-up TKI

  

0.155

  

 Yes

30

9.0 (5.4–12.6)

   

 No

53

5.0 (3.0–7.0)

   
  1. AFP Alpha fetoprotein, APS ArterioPortal Shunt, HVI Hepatic Vein Invasion, EHS Extra Hepatic Spread, TKI Tyrosine Kinase Inhibitor