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Table 4 Subgroup analysis of OS in mPVTT patients treated with DEB-TACE or C-TACE

From: Safety, efficacy, and survival of drug-eluting beads-transarterial chemoembolization vs. conventional-transarterial chemoembolization in advanced HCC patients with main portal vein tumor thrombus

Factors

Median OS in DEB-TACE (Months)

Median OS in C-TACE (Months)

P-Value

Child–Pugh

 A

13.0 (11.5–14.5)

4.0 (3.0–5.0)

 < 0.001

 B

9.0 (2.8–15.2)

10.0 (4.4–15.6)

0.997

AFP value

 ≤ 400 ng/ml

14.0 (8.9–19.1)

8.0 (3.9–12.1)

0.033

 > 400 ng/ml

12.0 (5.2–18.8)

4.0 (2.5–5.5)

0.001

APS

 Present

5.0 (3.0–7.0)

3.0 (2.1–3.9)

0.040

 Absent

14.0 (11.4–16.6)

9.0 (5.7–12.3)

0.001

HVI

 Present

12.0 (5.7–18.3)

4.0 (3.0–5.0)

0.003

 Absent

13.0 (9.1–16.9)

9.0 (4.8–13.2)

0.058

EHS

 Present

12.0 (4.1–19.6)

4.0 (3.1–4.9)

0.016

 Absent

12.0 (8.0–16.0)

6.0 (3.1–8.9)

0.007

Maximum Diameter

 ≤ 5 cm

14.0 (12.0–16.0)

12.0 (2.6–21.4)

0.254

 > 5 cm

12.0 (6.4–17.6)

5.0 (3.9–6.1)

 < 0.001

Capsular Infiltration

 Non-infiltration

18.0 (8.2–27.8)

9.0 (3.8–14.2)

0.001

 Infiltration

8.0 (4.2–11.8)

4.0 (2.4–5.6)

0.012

Tumor Numbers

 Single

14.0 (1.0–27.0)

4.0 (2.5–5.5)

0.668

 Multiple

12.0 (7.5–16.5)

5.0 (2.8–7.2)

 < 0.001

Tumor Response

 CR + PR + SD

14.0 (12.2–15.8)

9.0 (6.3–11.7)

0.001

 PD

4.0 (3.1–4.9)

4.0 (3.4–4.6)

0.590

  1. AFP alpha fetoprotein, APS ArterioPortal Shunt, HVI Hepatic Vein Invasion, EHS Extra Hepatic Spread, CR Complete Response, PR Partial Response, SD Stable Disease, PD Progression Disease