The solid component within part-solid nodules: 3-dimensional quantification, correlation with the malignant grade of nonmucinous pulmonary adenocarcinomas, and comparisons with 2-dimentional measures and semantic features in low-dose computed tomography

Table 4 Diagnostic performance of models in the training and testing cohorts

Models	AUC (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	Z	P ^a
Training cohort
Semantic	0.809 (0.753–0.856)	0.784 (0.713–0.845)	0.753 (0.642–0.844)	2.755	0.006
2-dimensional	0.821 (0.767–0.868)	0.728 (0.653–0.795)	0.818 (0.714–0.897)	3.097	0.002
CTRV_− 250HU	0.890 (0.843–0.927)	0.870 (0.809–0.918)	0.792 (0.685–0.876)	-	-
Testing cohort
Semantic	0.710 (0.603–0.802)	0.763 (0.634–0.864)	0.714 (0.513–0.868)	1.990	0.047
2-dimensional	0.760 (0.656–0.845)	0.661 (0.526–0.779)	0.750 (0.551–0.893)	2.108	0.035
CTRV_− 250HU	0.832 (0.737–0.904)	0.847 (0.730–0.928)	0.786 (0.590–0.917)	-	-

^a Comparison of AUC with 3-dimensional model. AUC, area under curve; CI, confidence interval

ISSN: 1470-7330