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Table 1 Characteristics of nonmucinous pulmonary adenocarcinomas that manifesting as part-solid nodules in the training cohort

From: The solid component within part-solid nodules: 3-dimensional quantification, correlation with the malignant grade of nonmucinous pulmonary adenocarcinomas, and comparisons with 2-dimentional measures and semantic features in low-dose computed tomography

Characteristic

MIA (n = 15)

IPA (n = 224)

P 1 a

r

P 2 b

Grade 1 (n = 62)

Grade 2 (n = 151)

Grade 3 (n = 11)

Gender

    

0.563

0.009

0.894

Male

4

24

48

5

   

Female

11

38

103

6

   

Age

47.5 ± 11.0

60.8 ± 9.3

58.5 ± 11.4

65.1 ± 10.8

< 0.001

0.088

0.174

Shape

    

0.999

0.007

0.917

Round/oval

0

2

4

0

   

Irregular

15

60

147

11

   

Margin

    

0.999

0.005

0.941

Smooth

0

1

2

0

   

Coarse

15

61

149

11

   

Lobulation

    

< 0.001

0.393

< 0.001

No

1

38

17

0

   

Yes

14

24

134

11

   

Spiculation

    

0.172

0.115

0.077

No

15

62

149

10

   

Yes

0

0

2

1

   

Pleural indentation

    

< 0.001

0.327

< 0.001

No

14

33

49

1

   

Yes

1

29

102

10

   

Air bronchogram

    

< 0.001

0.330

< 0.001

No

15

48

71

5

   

Yes

0

14

80

6

   

Vacuole

    

0.258

0.071

0.277

No

14

60

135

11

   

Yes

1

2

16

0

   

Vessel convergence

    

< 0.001

0.262

< 0.001

No

15

44

73

6

   

Yes

0

18

78

5

   

Maximal diameter (mm)

10.1 ± 2.5

17.6 ± 6.4

20.5 ± 7.0

24.0 ± 6.6

< 0.001

0.366

< 0.001

CTR (%)

38.6 ± 10.6

38.9 ± 13.1

53.4 ± 15.8

64.1 ± 14.1

< 0.001

0.456

< 0.001

Volume (mm3)

363.8 ± 266.0

2051.1 ± 2019.0

2770.3 ± 2305.2

3526.0 ± 2096.0

< 0.001

0.361

< 0.001

Mean attenuation (HU)

-598.3 ± 70.1

-578.5 ± 90.3

-426 ± 118.5

-331.4 ± 55

< 0.001

0.609

< 0.001

CTRV− 400HU (%)

11.6 ± 7.6

17.5 ± 13.1

42.9 ± 19.6

57.5 ± 8.9

< 0.001

0.636

< 0.001

CTRV− 350HU (%)

8.0 ± 5.6

13.5 ± 11.1

37.0 ± 18.9

51.7 ± 9.3

< 0.001

0.641

< 0.001

CTRV− 300HU (%)

5.2 ± 4.1

10.1 ± 9.2

31.5 ± 18.0

46.1 ± 9.5

< 0.001

0.650

< 0.001

CTRV− 250HU (%)

3.4 ± 2.9

7.5 ± 7.6

26.5 ± 16.7

40.6 ± 9.7

< 0.001

0.655

< 0.001

CTRV− 200HU (%)

1.8 ± 1.8

5.4 ± 6.1

21.8 ± 15.4

35 ± 9.8

< 0.001

0.654

< 0.001

CTRV− 150HU (%)

0.7 ± 1.2

3.7 ± 4.8

17.5 ± 13.9

29.5 ± 10.0

< 0.001

0.654

< 0.001

CTRV− 100HU (%)

0.3 ± 0.7

2.5 ± 3.6

13.6 ± 12.2

24.0 ± 10.4

< 0.001

0.647

< 0.001

CTRV− 50HU (%)

0.1 ± 0.2

1.4 ± 2.5

9.9 ± 10.4

18.7 ± 10.6

< 0.001

0.632

< 0.001

CTRV0HU (%)

0.0 ± 0.0

0.7 ± 1.4

6.4 ± 8.1

13.0 ± 9.5

< 0.001

0.611

< 0.001

CTRV50HU (%)

0.0 ± 0.0

0.2 ± 0.6

2.6 ± 4.1

5.6 ± 5.4

< 0.001

0.580

< 0.001

  1. a The group comparisons among different malignant grade of nonmucinous pulmonary adenocarcinomas. b The Spearman’s correlation analyses between characteristics and malignant grade of nonmucinous pulmonary adenocarcinomas. MIA, minimally invasive adenocarcinoma; IPA, invasive pulmonary adenocarcinoma; CTR, consolidation-to-tumor ratio; HU, Hounsfield unit; CTRV, consolidation/tumor ratio of volume
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Cancer Imaging

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