Table 6 Combined results of adjusted HRs
Imaging features | Subgroup | No. of studies | No. of patients | Forms of comparison | Primary endpoints | Overall/Event-Free Survival | Heterogeneity | P>|t| | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
HRs | 95%CI | I²(%) | PQ | ||||||||
Arterial phase enhancement pattern (2 Categories) | NA | 2 | 108 | Hypo/Hyper | OS | 2.01 | (1.16 | 3.50) | 5.2 | 0.304 | NA |
NA | 2 | 111 | Hypo/Hyper | EFS | 3.94 | (2.00 | 7.75) | 0.0 | 0.345 | NA | |
Invasion of bile duct | CT/ICC | 1 | 161 | Presence/Absence | OS | 1.19 | (0.76 | 1.86) | 0.0 | NA | 0.889 |
MRI/IMCC | 2 | 262 | 1.91 | (1.32 | 2.75) | 0.0 | 0.884 | ||||
Subtotal | 3 | 423 | 1.58 | (1.19 | 2.10) | 23.1 | 0.272 | ||||
Infiltrating tumor margin | NA | 2 | 405 | Presence/Absence | OS | 2.33 | (1.82 | 2.99) | 0.0 | 0.617 | NA |
NA | 2 | 394 | EFS | 1.94 | (1.43 | 2.65) | 3.1 | 0.310 | NA | ||
Arterial phase enhancement pattern (3 Categories) | NA | 4 | 394 | Hypo/Hyper | OS | 5.90 | (3.40 | 10.00) | 8.0 | NA | NA |
Rim/Hyper | 2.60 | (1.60 | 4.30) | ||||||||
5 | 533 | Hypo/Hyper | EFS | 3.80 | (2.50 | 5.60) | 22.0 | NA | |||
Rim/Hyper | 2.90 | (2.00 | 4.10) | ||||||||