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Table 2 Association between imaging findings location with PSMA- and/or Choline-PET/CT and treatment decision. Salvage radiotherapy (sRT); Androgen deprivation therapy (ADT).

From: Influence of molecular imaging on patient selection for treatment intensification prior to salvage radiation therapy for prostate cancer: a post hoc analysis of the PROPS trial

  

Therapeutic decision

  

sRT

ADT ± sRT

  

Location

n/N

%

n/N

%

Odds Ratio

(95% CI)

P-value1

Molecular imaging findings

Extraprostatic

Fossa

Negative

6/13

6/10

40/50

46.2

60.0

80.0

7/13

4/10

10/50

53.8

40.0

20.0

4.67(1.28;16.99)

2.67(0.63;11.28)

0.0490*

Positive

Negative

12/23

40/50

52.2

80.0

11/23

10/50

47.8

20.0

3.67(1.25;10.71)

0.0175*

Metastatic

Non-metastatic

6/13

46/60

46.2

76.7

7/13

14/60

53.8

23.3

3.83(1.11;13.30)

0.0342*

  1. 1Based on Bivariate Logistic Regression with Wald confidence interval, and Firth Correction for bias (C) when
  2. appropriate. * <0.05