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Table 2 Patient characteristics of the PTC with LLNM and PTC without LLNM groups in the training cohort

From: Nomogram for preoperative estimation risk of lateral cervical lymph node metastasis in papillary thyroid carcinoma: a multicenter study

Characteristic

Non-LLNM group (% )

LLNM group (% )

p

n

1358

374

Ā 

Age (years)

Ā Ā 

0.016

ā‰¤ā€‰55

1126 (82.9)

330 (88.2)

Ā 

>55

232 (17.1)

44 (11.8)

Ā 

Gender, n

Ā Ā 

0.0028

Female

1068 (78.6)

266 (71.1)

Ā 

Male

290 (21.4)

108 (28.9)

Ā 

Tumor size (cm)

Ā Ā 

<0.0001

c

515 (37.9)

60 (16.0)

Ā 

>1 and ā‰¤ā€‰2

709 (52.2)

199 (53.2)

Ā 

>2 and ā‰¤ā€‰3

133 (9.8)

99 (26.5)

Ā 

>3

1 (0.1)

16 (4.3)

Ā 

Tumor position

Ā Ā 

<0.0001

Upper pole

377 (27.8)

151 (40.4)

Ā 

Middle pole

350 (25.8)

82 (21.9)

Ā 

Lower pole

588 (43.3)

134 (35.8)

Ā 

Isthmus

43 (3.1)

7 (1.9)

Ā 

Composition

Ā Ā 

0.0631

Mixed cystic and solid

9 (0.7)

7 (1.9)

Ā 

Solid

1349 (99.3)

367 (98.1)

Ā 

Internal echo

Ā Ā 

0.0011

Hyper or isoechoic

17 (1.3%)

8 (2.2)

Ā 

Hypoechoic

903 (66.5)

281 (75.1)

Ā 

Markedly hypoechoic

438 (32.2)

85 (22.7)

Ā 

Margins

Ā Ā 

0.836

Well-defined

101 (7.4)

26 (7.0)

Ā 

Ill-defined

1257 (92.6)

348 (93.0)

Ā 

Shape

Ā Ā 

0.0737

Ā A/Tā€‰<ā€‰1

318 (23.4)

105 (28.1)

Ā 

A/Tā€‰ā‰„ā€‰1

1040 (76.6)

269 (71.9)

Ā 

Microcalcification

Ā Ā 

<0.0001

No

327 (24.1)

34 (9.1)

Ā 

Yes

1031 (75.9)

340 (90.9)

Ā 

Vascularization (blood flow)

Ā Ā 

0.0002

0

964 (71.0)

229 (61.2)

Ā 

1

244 (18.0)

86 (23.0)

Ā 

2

106 (7.8)

51 (13.6)

Ā 

3

44 (3.2)

8 (2.2)

Ā 

Abutment/perimeter

Ā Ā 

<0.0001

ā‰¤ā€‰0.25

731 (53.8)

58 (15.5)

Ā 

>ā€‰0.25

627 (46.2)

316 (84.5)

Ā 

Mulifocality

Ā Ā 

<0.0001

No

930 (68.5)

172 (46.0)

Ā 

Yes

428 (31.5)

202 (54.0)

Ā 

Hashimoto thyroiditis

Ā Ā 

0.2229

Negative

1056 (77.8)

279 (74.6)

Ā 

Positive

302 (22.2)

95 (25.4)

Ā 

BRAF V600E mutation

Ā Ā 

0.0570

No

181 (13.3)

65 (17.4)

Ā 

Yes

1177 (86.7)

309 (82.6)

Ā 
  1. Noteā€”LLNM, lateral lymph node metastases; A/Tā€‰<ā€‰1, wider-than-tall; A/Tā€‰ā‰„ā€‰1, taller than wide