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Table 1 Patient Characteristics

From: A prediction model of nodal metastasis in cN0 oral squamous cell carcinoma using metabolic and pathological variables

 

Training cohort(n = 95)

 

Validation cohort(n = 46)

 

Variables

Nodal metastasis ( −)

n = 57

Nodal metastasis ( +)

n = 38

P

Nodal metastasis ( −)

n = 32

Nodal metastasis ( +)

n = 14

P

Age(year)

63.6 ± 12.4

60.6 ± 11.7

0.277

61.0 ± 12.3

65.0 ± 8.1

0.226

Gender(male:female)

42:15

33:5

0.123

22:10

11:3

0.496

Drinker(No vs Yes)

47:10

26:12

0.112

23:9

13:1

0.112

Smoker(No vs Yes)

39:18

24:14

0.595

20:12

11:3

0.285

Clinical T stage

 I: II: III

23:28:6

4:26:8

0.006

11:19:2

2:8:4

0.077

Grade of tumor

 Low: Moderate: Poor

6:51:0

0:32:6

0.001

5:26:1

0:13:1

0.259

Pathological Tumor size(cm)

2.5(1.0–6.0)

3.8(1.0–6.0)

0.000

3.0(1.0–5.0)

3.3(2.0–7.0)

0.140

Depth of invasion

5 mm: > 5 mm,10 mm: > 10 mm

20:16:21

3:2:33

0.000

12:6:14

0:5:9

0.027

Pathological T stage

 I: II: III

14:22:21

1:4:33

0.000

10:11:11

0:4:10

0.025

Margin(negative vs positive)

56:1

32:2

0.286

32:0

13:1

0.304

Perineural invasion(No vs Yes)

46:11

19:15

0.011

28:4

8:6

0.022

Lymphovascular invasion(No vs Yes)

57:0

36:2

0.157

32:0

14:0

 

Tumor SUVmax

12.3(3.0–32.4)

13.7(3.7–31.7)

0.020

8.9(2.1–49.7)

8.8(1.4–27.6)

0.830

Tumor SUVmean

5.9(1.8–16.8)

7.6(2.9–19.3)

0.015

5.4(1.4–32.6)

4.8(0.8–17.5)

0.933

Heterogeneity indexa

1.7(1.1–2.6)

1.7(1.3–2.0)

0.312

1.6(1.5–1.8)

1.7(1.6–1.9)

0.403

Tumor MTV(cm3)

4.3(0.8–50.7)

9.0(2.0–70.3)

0.000

4.6(1.1–26.6)

6.3(2.1–93.4)

0.050

Tumor TLG

28.7(3.3–411.6)

75.2(10.3–1052.7)

0.000

25.6(3.3–156.1)

37.3(8.3–463.0)

0.166

Nodal long diameter(cm)

0.9(0.4–1.3)

1.0(0.5–1.2)

0.135

0.9(0.6–1.2)

1.0(0.7–1.2)

0.933

Nodal short diameter(cm)

0.6(0.3–1.1)

0.7(0.4–1.1)

0.000

0.7(0.3–1.1)

0.8(0.4–0.9)

0.193

Nodal SUVmax

2.2(0.5–5.2)

3.7(1.1–10.6)

0.000

1.9(0.9–4.5)

2.66(1.1–15.7)

0.079

  1. aHeterogeneity index = Tumor SUVmax/Tumor SUVmean