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Table 1 Clinical characteristics of 583 nasopharyngeal carcinoma patients

From: Prognostic significance of cervical radiologic carotid artery invasion by lymph node on magnetic resonance imaging in nasopharyngeal carcinoma

Variables

N0 (nā€‰=ā€‰89, 15.3%)

Nā€‰+ā€‰patients (nā€‰=ā€‰494, 84.7%)

Non-rCAI (nā€‰=ā€‰285, 57.7%)

rCAI (nā€‰=ā€‰209, 42.3%)

P

Gender

Ā Ā Ā 

0.007

ā€ƒMale

68 (76.4)

192 (67.4)

164 (78.5)

Ā 

ā€ƒFemale

21 (23.6)

93 (32.6)

45 (21.5)

Ā 

Age

Ā Ā Ā 

0.911

ā€‰ā€ƒā‰¤ā€‰47Ā years

45 (50.6)

146 (51.2)

106 (50.7)

Ā 

ā€‰ā€ƒ>ā€‰47Ā years

44 (49.4)

139 (48.8)

103 (49.3)

Ā 

Histologic type

Ā Ā Ā 

0.646

ā€ƒKSCC

0

1 (0.4)

2 (1.0)

Ā 

ā€ƒNKDC

1 (1.1)

13 (4.6)

11 (5.3)

Ā 

ā€ƒNKUC

88 (98.9)

271 (95.0)

196 (93.7)

Ā 

T stage

Ā Ā Ā 

0.701

ā€ƒT1

7 (7.9)

20 (7.0)

16 (7.7)

Ā 

ā€ƒT2

27 (30.3)

70 (24.5)

56 (26.7)

Ā 

ā€ƒT3

38 (42.7)

131 (46.0)

99 (47.4)

Ā 

ā€ƒT4

17 (19.1)

64 (22.5)

38 (18.2)

Ā 

N stage

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒN0

89 (100)

Ā Ā Ā 

ā€ƒN1

Ā 

156 (54.7)

44 (21.1)

Ā 

ā€ƒN2

Ā 

107 (37.5)

76 (36.4)

Ā 

ā€ƒN3

Ā 

22 (7.8)

89 (42.5)

Ā 

Total stage

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒI

7 (7.9)

Ā Ā Ā 

ā€ƒII

27 (30.3)

42 (14.7)

8 (3.8)

Ā 

ā€ƒIII

38 (42.7)

162 (56.8)

87 (41.6)

Ā 

ā€ƒIV

17 (19.1)

81 (28.5)

114 (54.5)

Ā 

Chemotherapy

Ā Ā Ā 

0.001

ā€ƒRT alone

10 (11.2)

Ā Ā Ā 

ā€ƒCCRT alone

32 (36.0)

44 (15.4)

12 (5.7)

Ā 

ā€ƒCCRTā€‰+ā€‰NAC/AC

47 (52.8)

241 (84.6)

197 (94.3)

Ā 

Laterality of cervical positive LNs

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒRLNs only

-

59 (20.7)

0 (0)

Ā 

ā€ƒUnilateral

-

100 (35.1)

74 (35.4)

Ā 

ā€ƒBilateral

-

126 (44.2)

135 (64.6)

Ā 

Location of positive LNs

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒUpper neck only

-

265 (93.0)

143 (68.4)

Ā 

ā€ƒUpperā€‰+ā€‰lower neck

-

20 (7.0)

66 (31.6)

Ā 

Size of positive LNs

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€‰ā€ƒā‰¤ā€‰6Ā cm

-

279 (97.9)

156 (74.6)

Ā 

ā€‰ā€ƒ>ā€‰6Ā cm

-

6 (2.1)

53 (25.4)

Ā 

CNN

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒNo

-

236 (82.8)

87 (41.6)

Ā 

ā€ƒYes

-

49 (17.2)

122 (58.4)

Ā 

rENE

Ā Ā Ā 

ā€‰<ā€‰0.001

ā€ƒNo

-

157 (55.1)

4 (1.9)

Ā 

ā€ƒYes

-

128 (44.9)

205 (98.1)

Ā 
  1. Abbreviations: rCAI radiological carotid artery invasion, KSCC keratinizing squamous cell carcinoma, NKDC non-keratinizing differentiated carcinoma, NKUC non-keratinizing undifferentiated carcinoma, RT radiotherapy, CCRT concurrent chemoradiotherapy, NAC neoadjuvant chemotherapy, AC adjuvant chemotherapy, LN lymph node, RLN retropharyngeal lymph node, CNN cervical node necrosis, rENE radiological extranodal extension