The diagnostic value of contrast-enhanced ultrasonography in breast ductal abnormalities

Cancer Imaging

Table 5 Receiver operating characteristic analysis of US and CEUS

Characteristic	SEN %	SPE %	PPV %	NPV %	ACC %	AUC	P	95% CI
Characteristic	SEN %	SPE %	PPV %	NPV %	ACC %	AUC	P	Lower	Upper
Enhancement scope(enlarged)	78.4	92.7	90.1	82.6	85.9	0.86	< 0.001	0.764	0.947
Microcalcification	42.1	95.5	88.9	65.6	70.7	0.69	0.040	0.567	0.810
Enhancement scope combined Microcalcifications	89.5	88.6	87.2	90.7	89.0	0.924	< 0.001	0.859	0.988

CI indicates confidence interval, SEN sensitivity, SPE specificity, PPV positive predictive value, NPV negative predictive value, ACC accuracy, AUC area under receiver. AUC_{enhancement scope + calcifications} vs. AUC_{microcalcification}, P < 0.0005; AUC_{enhancement scope + microcalcifications} vs. AUC_{enhancement scope}, P = 0.007; AUC_{microcalcifications} vs. AUC_{enhancement scope}, P = 0.011

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