Table 1 Characteristics of patients in the ALK-positive and ALK-negative groups
Variables | ALK+ (n = 65) | ALK- (n = 629) | Χ2(t) | P-value |
|---|---|---|---|---|
Age (years) Mean ± SD (range) | 55.86 ± 9.41 (33–73) | 58.55 ± 9.72 (23–81) | −2.133 | 0.033a |
 ≥ 60 y | 24 (36.9) | 313 (49.8) | 3.887 | 0.049 |
 < 60 y | 41 (63.1) | 316 (50.2) | 3.887 | 0.049 |
Sex | Â | Â | 0.024 | 0.876 |
 Male | 29 (44.6) | 287 (45.6) |  |  |
 Female | 36 (55.4) | 342 (54.4) |  |  |
Smoking | Â | Â | 1.913 | 0.167 |
 Nonsmoker | 13 (20.0) | 176 (28.0) |  |  |
 Smoker | 52 (80.0) | 452 (72.0) |  |  |
Family history of lung cancer | 8 (12.3) | 87 (13.9) | 0.119 | 0.730 |
 CEA level |  |  | 4.009 | 0.050 |
 Normal (0–5 ng/mL) | 1 (1.5) | 54 (8.6) |  |  |
 Abnormal (> 5 ng/mL) | 64 (98.5) | 575 (91.4) |  |  |