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Table 1 Clinicopathological and MRI characteristics of patients with sarcomatoid renal cell carcinoma

From: Sarcomatoid renal cell carcinoma: MRI features and their association with survival

Characteristics

Category

No. of patients (%)a

Clinicopathological findings

  Age (years)

62 (51, 68)a

  Gender

Male

41 (69.5)

Female

18 (30.5)

  Ethnicity

White

47 (79.7)

Black

2 (3.4)

Asian

6 (10.2)

Unknown

4 (6.8)

  Baseline metastatic status

Loco-regional

33 (55.9)

Metastatic

26 (44.1)

  Nephrectomy type

Radical

49 (83.1)

Partial

10 (16.9)

  Lymph node dissection

Standard

31 (52.5)

Extended

11 (18.6)

None

17 (28.8)

  Systemic treatmentsb

None (only nephrectomy)

14 (23.7)

Neoadjuvant only

2 (3.4)

Neoadjuvant and adjuvant

6 (10.2)

Adjuvant

37 (62.7)

  Pathological tumor size (cm)

105 (7.7, 12.8)a

  Pathological tumor stage

pT1

4 (6.8)

pT2

8 (13.6)

pT3

43 (72.9)

pT4

4 (6.8)

  Histological subtype

Clear cell

44 (74.6)

Papillary

2 (3.4)

Chromophobe

6 (10.2)

Othersc

7 (11.8)

  Metastatic lymph nodes

on pathology

Present

13 (22.4)

Absent

46 (77.6)

MRI findings

  Size on MRI (cm)

10.5 (7.5, 12.7)a

  Non-enhancing areas

Present

50 (84.7)

Absent

9 (15.3)

  Lymphadenopathy

Present

17 (28.8)

Absent

42 (71.2)

  T2LIA volume (ml)

3.0 (0.1, 13.0)a

  Percentage of T2LIA (%)

0.8 (0.0, 2.9)a

  1. aPresented as median and interquartile range; others are presented as number of patients and percentages
  2. bNivolumab alone (n = 7), ipilimumab and nivolumab (n = 8), or nivolumab and pembrolizumab (n = 2)
  3. cUnclassified (n = 3), collecting duct type (n = 2) and fumarate-dehydratase deficient (n = 2)