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Table 3 MR Imaging features of iCCA

From: Preoperative subcategorization based on magnetic resonance imaging in intrahepatic cholangiocarcinoma

Imaging features

Subtype

Small duct type (n = 63)

Large duct type (n = 30)

p value

Intratumoral hemorrhage a

2 (3.2%)

2 (6.7%)

0.438

Targetoid restriction

31 (49.2%)

4 (13.3%)

0.001*

Restricted diffusion

63 (100%)

32 (100%)

> 0.999

Arterial enhancement pattern

 Arterial phase hypoenhancement

3 (4.8%)

9 (30%)

0.001

 Rim APHE

48 (76.2%)

17 (56.7%)

0.055

 Non-rim APHE

12 (19.0%)

4 (13.3%)

0.495

T2-weighted signal intensity

 Diffused iso- / mild-hyperintense

20 (31.7%)

15 (50.0%)

0.089

 Diffused marked hyperintense

19 (30.2%)

13 (43.3%)

0.211

 Targetoid appearance in T2

24 (38.1%)

2 (6.7%)

0.002*

Peripheral washout

19 (30.2%)

4 (13.3%)

0.079

Non-peripheral washout a

5 (7.9%)

1 (3.3%)

0.372

Delayed enhancement

54 (85.7%)

26 (86.7%)

0.901

Corona enhancement

25 (39.7%)

8 (26.7%)

0.220

Enhancing capsule a

8 (12.7%)

3 (10.0%)

0.706

Tumor in vein a

4 (6.3%)

7 (23.3%)

0.018*

Intrahepatic duct dilatation

11 (17.5%)

23 (76.7%)

< 0.001*

Hepatic capsule retraction

29 (46.0%)

11 (36.7%)

0.394

  1. iCCA Intrahepatic cholangiocarcinoma, APHE Arterial phase hyperenhancement, LR LI-RADS
  2. a data were compared by Fisher’s exact test. *p <  0.05