Skip to main content

Table 4 Diagnostic performance of CECT and EOB-MRI for detecting viable HCC with corresponding histopathologic abnormality

From: Prospective evaluation of Gadoxetate-enhanced magnetic resonance imaging and computed tomography for hepatocellular carcinoma detection and transplant eligibility assessment with explant histopathology correlation

Size

 

CECT

EOB-MRI

P-value

Se

Sp

NPV

PPV

Acc

Se

Sp

NPV

PPV

Acc

Sen

Sp

overall

R1

58.3 (21/36)

86.6 (58/67)

79.5 (58/73)

70 (21/30)

76.7 (79/103)

66.7 (22/33)

88.5 (54/61)

83.1 (54/65)

75.9 (22/29)

80.9 (76/94)

  

R2

54.5 (18/33)

91.7 (66/72)

81.5 (66/81)

75 (18/24)

80 (84/105)

60 (21/35)

95.8 (69/72)

83.1 (69/83)

87.5 (21/24)

84.1 (90/107)

  

Pooled

56.5

89.2

   

63.2

92.5

   

0.312

0.312

<  2 cm

R1

81 (17/21)

50 (9/18)

69.2 (9/13)

65.4 (17/26)

66.7 (26/39)

87.5 (14/16)

50 (7/14)

77.8 (7/9)

66.7 (14/21)

70 (21/30)

  

R2

66.7 (10/15)

75 (12/16)

70.6 12/17)

71.4 10/14)

71 (22/31)

82.4 (14/17)

83.3 (10/12)

76.9 (10/13)

87.5 (14/16)

82.8 (24/29)

  

Pooled

75

61.8

   

84.8

65.4

   

0.037

0.037

≥ 2 cm

R1

26.7 (4/15)

100 (49/49)

81.7 (49/60)

100 (4/4)

82.8 (53/64)

47.1 (8/17)

100 (45/45)

83.3 (45/54)

100 (8/8)

85.5 (53/62)

  

R2

44.4 (8/18)

96.4 (54/56)

84.4 54/64)

80 8/10)

83.8 (62/74)

38.9 (7/18)

98.3 (59/60)

84.3 (59/70)

87.5 (7/8)

84.6 (66/78)

  

Pooled

36.4

98.1

   

42.9

99

   

0.504

0.504

  1. Data are percentages, with numerators and denominators in parentheses
  2. Acc accuracy, CECT contrast-enhanced computed tomography, EOB-MRI Gadoxetic acid-enhanced MRI, NPV negative predictive value, PPV positive predictive value, R1 reader 1, R2 reader 2, Se sensitivity, Sp specificity