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Table 3 Factors associated with disease-free survival on the Cox proportional hazards model

From: Prognostic impact of 18F-FDG PET/CT in pathologic stage II invasive ductal carcinoma of the breast: re-illuminating the value of PET/CT in intermediate-risk breast cancer

 

Disease-free survival

Univariate

Multivariate

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Age, years

 

0.451

  

 ≥ 40

1.00 (reference)

   

 < 40

1.58 (0.48–5.13)

   

Ki-67

 

0.426

  

 < 14

1.00 (reference)

   

 ≥ 14

1.62 (0.50–5.26)

   

Hormonal therapy

 

0.011

 

0.639

 Yes

1.00 (reference)

 

1.00 (reference)

 

 No

2.31 (1.21–4.44)

 

1.31 (0.43–3.97)

 

HER2-targeted agent

 

0.570

  

 Yes

1.00 (reference)

   

 No

1.75 (0.62–4.95)

   

Adjuvant chemotherapy

 

0.014

 

0.051

 Yes

1.00 (reference)

 

1.00 (reference)

 

 No

3.28 (1.27–8.45)

 

2.58 (0.99–6.68)

 

TNM stage

 

0.109

  

 IIA

1.00 (reference)

   

 IIB

1.71 (0.89–3.30)

   

Pathologic prognostic stage

 

0.046

 

0.324

 I

1.00 (reference)

 

1.00 (reference)

 

 II

1.68 (0.84–3.37)

 

0.99 (0.33–2.98)

 

 III

3.82 (1.39–10.51)

 

2.19 (0.50–9.66)

SUVmax

 

0.004

 

0.948

 ≤ 12.8

1.00 (reference)

 

1.00 (reference)

 

 > 12.8

3.03 (1.43–6.43)

 

1.04 (0.34–3.16)

 

SUVpeak

 

<  0.001

 

0.007

 ≤ 8.2

1.00 (reference)

 

1.00 (reference)

 

 > 8.2

3.46 (1.78–6.74)

 

2.58 (1.29–5.15)

 

TLR

 

0.012

 

0.078

 ≤ 2.1

1.00 (reference)

 

1.00 (reference)

 

 > 2.1

3.81 (1.35–10.77)

 

2.65 (0.90–7.82)

 

MTV (cm3)

 

0.001

 

0.241

 ≤ 5.1

1.00 (reference)

 

1.00 (reference)

 

 > 5.1

3.10 (1.63–5.93)

 

1.60 (0.73–3.49)

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