Evaluation of integrin αvβ3-targeted imaging for predicting disease progression in patients with high-risk differentiated thyroid cancer (using 99mTc-3PRGD2)

Table 4 Sites of lesion detection and radiotracer uptake parameters on ^99mTc-3PRGD₂ SPECT/CT

Site	Number of patients	Number of lesions	T/B ratio			SUV_max
Site	Number of patients	Number of lesions	Median	Mean ± SD	Range	Median	Mean ± SD	Range
Thyroid bed	2	2	4.04	4.04 ± 0.61	3.60–4.47	3.51	3.51 ± 0.35	3.26–3.76
Nodal	22	37	2.73	3.05 ± 1.39	1.15–7.68	3.25	3.66 ± 1.85	1.20–9.11
Lungs	5	Multiple	2.72	4.50 ± 5.74	1.06–20.43	3.73	7.94 ± 11.34	2.04–30.99

Abbreviations: T/B ratio tumor-to-background ratio, SUV_max maximum standardized uptake value

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