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Fig. 2 | Cancer Imaging

Fig. 2

From: Evaluation of integrin αvβ3-targeted imaging for predicting disease progression in patients with high-risk differentiated thyroid cancer (using 99mTc-3PRGD2)

Fig. 2

Representative 99mTc-3PRGD2 SPECT/CT images of patients with 131I negative and 99mTc-3PRGD2 positive lesions. A 99mTc-3PRGD2 SPECT/CT detected lung metastases in a 63-year-old female PTC patient with initial TSH-stimulated Tg 3.1 ng/ml and positive TgAb. 99mTc-3PRGD2 SPECT/CT showed a focal uptake in the right pulmonary nodule. B 131I post therapy WBS showed no uptake in this pulmonary nodule. C 99mTc-3PRGD2 SPECT/CT detected lymph node metastases in a 41-year-old female PTC patient with initial TSH-stimulated Tg > 500 ng/ml. 99mTc-3PRGD2 SPECT/CT showed focal uptakes in left cervical lymph nodes (level II and IV). The diffuse 99mTc-3PRGD2 accumulation in thyroid bed was considered to be caused by postsurgical reactions. D 131I post therapy WBS showed no uptake in these lymph nodes. These neck lymph nodes were positive for metastatic PTC on histopathologic examination after secondary surgery

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Cancer Imaging

ISSN: 1470-7330

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