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Table 2 Diagnostic performance for IVIM-DKI indexes and their combinations in assessing radiotherapeutic response

From: Intravoxel incoherent motion imaging combined with diffusion kurtosis imaging to assess the response to radiotherapy in a rabbit VX2 malignant bone tumor model

Variable

Youden Index

AUC

(95%CI)

Sensitivity (%)

Specificity (%)

Dt

0.556

0.802

(0.623–0.921)

55.56

100.00

fp

0.452

0.742

(0.558–0.880)

66.67

78.57

MK

0.532

0.762

(0.579–0.894)

88.89

64.29

Dt and fp

0.579

0.857

(0.688–0.955)

72.22

85.71

Dt and MK

0.691

0.905

(0.748–0.980)

83.33

85.71

fp and MK

0.508

0.798

(0.619–0.918)

72.22

78.57

Dt and fp and MK

0.746

0.913

(0.758–0.983)

88.89

85.71

  1. Dt Tissue diffusion, fp Perfusion fraction, Dp Pseudo-diffusion, MK Mean kurtosis, MD Mean diffusion coefficient