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Table 1 Summary of Diffusion Parameters in each group

From: Intravoxel incoherent motion imaging combined with diffusion kurtosis imaging to assess the response to radiotherapy in a rabbit VX2 malignant bone tumor model

Variable

Pre-treatment

Post-treatment

P1

P2

P3

Considerable effect

Slight effect

Dt(× 10− 3 mm2/s)

0.71 ± 0.06

0.95 ± 0.06

0.88 ± 0.04

< 0.001

< 0.001

0.007

fp(%)

8.44 ± 0.59

6.51 ± 0.77

7.14 ± 0.69

< 0.001

< 0.001

0.036

Dp(×10− 3 mm2/s)

6.91 ± 1.50

7.17 ± 2.31

8.19 ± 1.99

0.929

0.207

0.330

MK

0.95 ± 0.08

0.73 ± 0.06

0.79 ± 0.07

< 0.001

< 0.001

0.031

MD(×10−3 mm2/s)

0.77 ± 0.08

1.04 ± 0.10

0.99 ± 0.06

< 0.001

< 0.001

0.042

TCD (%)

43.55 ± 4.86

19.15 ± 3.40

33.58 ± 11.10

< 0.001

< 0.001

< 0.001

  1. P1: Pre-treatment vs. Considerable effect, P2: Pre-treatment vs. Slight effect, P3: Considerable effect vs. Slight effect
  2. Dt Tissue diffusion, fp Perfusion fraction, Dp Pseudo-diffusion, MK Mean kurtosis, MD Mean diffusion coefficient, TCD Tumor cell density