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Table 4 Inter-observer classification for perfusion parameters of differently shaped regions of interest and in different areas in glioma patients in the post-treatment group

From: Reliability of dynamic susceptibility contrast perfusion metrics in pre- and post-treatment glioma

 

Perfusion metric

Intraclass Correlation

95%-Confidence interval

P-value

Lower Bound

Upper Bound

Whole tumor region; Post-treatment group of patients; Circular ROI

CBF

0.555

0.062

0.810

0.017

CBV

0.720

0.410

0.880

 < 0.001

TTP

0.331

-0.409

0.715

0.143

Tumor hotspot; Post-treatment group of patients; Circular ROI

CBF

-0.260

-1.653

0.462

0.700

CBV

-0.389

-1.926

0.407

0.776

TTP

-0.218

-1.566

0.480

0.671

Peritumoral region; Post-treatment group of patients; Circular ROI

CBF

-0.014

-1.137

0.567

0.497

CBV

-0.048

-1.207

0.553

0.529

TTP

-0.023

-1.155

0.563

0.505

Whole tumor region; Post-treatment group of patients; Polygonal ROI

CBF

-0.021

-1.150

0.564

0.503

CBV

0.083

-0.932

0.609

0.397

TTP

0.034

-1.034

0.588

0.448

Tumor hotspot; Post-treatment group of patients; Polygonal ROI

CBF

-0.025

-1.158

0.563

0.506

CBV

-0.087

-1.290

0.563

0.565

TTP

0.102

-0.891

0.617

0.377

Peritumoral region; Post-treatment group of patients; Polygonal ROI

CBF

-0.086

-1.288

0.536

0.564

CBV

-0.032

-1.174

0.559

0.514

TTP

-0.032

-1.173

0.560

0.513

  1. CBV Cerebral blood volume, ICC Intraclass correlation coefficient, CBF Cerebral blood flow, TTP Time-to-peak