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Table 4 Inter-observer classification for perfusion parameters of differently shaped regions of interest and in different areas in glioma patients in the post-treatment group

From: Reliability of dynamic susceptibility contrast perfusion metrics in pre- and post-treatment glioma

  Perfusion metric Intraclass Correlation 95%-Confidence interval P-value
Lower Bound Upper Bound
Whole tumor region; Post-treatment group of patients; Circular ROI CBF 0.555 0.062 0.810 0.017
CBV 0.720 0.410 0.880  < 0.001
TTP 0.331 -0.409 0.715 0.143
Tumor hotspot; Post-treatment group of patients; Circular ROI CBF -0.260 -1.653 0.462 0.700
CBV -0.389 -1.926 0.407 0.776
TTP -0.218 -1.566 0.480 0.671
Peritumoral region; Post-treatment group of patients; Circular ROI CBF -0.014 -1.137 0.567 0.497
CBV -0.048 -1.207 0.553 0.529
TTP -0.023 -1.155 0.563 0.505
Whole tumor region; Post-treatment group of patients; Polygonal ROI CBF -0.021 -1.150 0.564 0.503
CBV 0.083 -0.932 0.609 0.397
TTP 0.034 -1.034 0.588 0.448
Tumor hotspot; Post-treatment group of patients; Polygonal ROI CBF -0.025 -1.158 0.563 0.506
CBV -0.087 -1.290 0.563 0.565
TTP 0.102 -0.891 0.617 0.377
Peritumoral region; Post-treatment group of patients; Polygonal ROI CBF -0.086 -1.288 0.536 0.564
CBV -0.032 -1.174 0.559 0.514
TTP -0.032 -1.173 0.560 0.513
  1. CBV Cerebral blood volume, ICC Intraclass correlation coefficient, CBF Cerebral blood flow, TTP Time-to-peak