Skip to main content

Table 3 Inter-observer classification for perfusion parameters of differently shaped regions of interest and in different areas in glioma patients prior to treatment

From: Reliability of dynamic susceptibility contrast perfusion metrics in pre- and post-treatment glioma

  Perfusion metric Intraclass Correlation 95%-Confidence interval P-value
Lower Bound Upper Bound
Whole tumor region; Untreated group of patients; Circular ROI CBF 0.963 0.924 0.984  < 0.001
CBV 0.948 0.892 0.977  < 0.001
TTP 0.951 0.899 0.979  < 0.001
Tumor hotspot; Untreated group of patients; Circular ROI CBF 0.441 -0.156 0.756 0.058
CBV 0.501 -0.032 0.782 0.030
TTP 0.198 -0.658 0.649 0.269
Peritumoral region; Untreated group of patients; Circular ROI CBF 0.821 0.630 0.922  < 0.001
CBV 0.924 0.843 0.967  < 0.001
TTP 0.741 0.465 0.887  < 0.001
Whole tumor region; Untreated group of patients;Polygonal ROI CBF 0.504 -0.026 0.783 0.029
CBV 0.687 0.352 0.863 0.001
TTP 0.856 0.703 0.937  < 0.001
Tumor hotspot; Untreated group of patients; Polygonal ROI CBF 0.828 0.644 0.925  < 0.001
CBV 0.529 0.027 0.794 0.021
TTP 0.200 -0.655 0.650 0.268
Peritumoral region; Untreated group of patients; Polygonal ROI CBF 0.442 -0.154 0.756 0.057
CBV 0.409 -0.223 0.742 0.078
TTP 0.113 -0.834 0.612 0.363
  1. CBV Cerebral blood volume, ICC Intraclass correlation coefficient, CBF Cerebral blood flow, TTP Time-to-peak