Fig. 9

A patient with prior history of adenocarcinoma of the prostate with rapidly progressive obstructive uropathy with multiple progressive liver lesions. The biopsy of the prostate and a liver lesion was consistent with neuroendocrine differentiation of prostate cancer. ⁶⁸Ga-DOTATATE PET (A), CT and PET/CT (B) showed multiple intensely tracer avid hepatic lesions (brackets) with lower activity in the prostate and scattered bone metastases (arrowheads). A patient with Merkel cell carcinoma with progression on multiple lines of therapy including immunotherapy, chemotherapy, targeted therapy with ⁶⁸Ga-DOTATATE PET (C), CT and PET/CT (D) showing intensely tracer avid lymphadenopathy in the right external iliac and inguinal regions (arrows)